Патологические рефлексы в области лица остаются объектом многочисленных исследований [1-9]. Актуальность темы обусловлена тем, что клиническое значение отдельных рефлексов не всегда очевидно, поскольку их можно обнаружить как у пациентов с заболеваниями нервной системы, так и здоровых взрослых [10, 11]. В связи с этим патологический характер выявленных рефлексов может вызвать сомнение. Одним из таких рефлексов является ладонно-подбородочный рефлекс Маринеско-Радовичи (ЛПР) [12]. ЛПР проявляется непроизвольным сокращением подбородочной мышцы и подтягиванием вверх кожи подбородка в ответ на механическое раздражение кожи возвышения большого пальца [10, 13]. Как правило, подбородочная мышца сокращается на стороне нанесения стимула (ипсилатерально).
Headaches are a common neurological complaint during pregnancy. Most are primary and benign but secondary headaches may also occur. In the first trimester, the complaints are mainly due to primary headaches, and in the last trimester, the proportion of secondary headaches increases. This article provides clinical characteristics of secondary headaches during pregnancy. The limited range of drugs that can be used during pregnancy, in the absence of potential adverse effects on the mother and fetus/newborn, causes certain difficulties in the management of these patients. This review will consider approaches to the treatment of headaches during pregnancy. A non-drug therapeutic strategy is preferred for the treatment of primary headaches during pregnancy. Treatment should not be delayed because uncontrolled headaches can have negative effects on both the mother and the fetus. If non-drug therapy does not lead to the expected control of headache attacks, a choice should be made regarding the use of drug therapy while weighing the benefits and risks of such a choice.
Objective: to demonstrate the mutual influence of the quality of patients’s life during epilepsy, adherence to received anticonvulsant therapy and retention on therapy.Material and methods. We conducted an analytical review of studies published by foreign authors in recent years (published within 2016–2021 were considered of top priority), devoted to the influence of various factors on adherence to therapy in patients with epilepsy. A search for relevant publications was conducted in English-language databases (PubMed/MEDLINE, ClinicalKey) by using key words and phrases: “epilepsy AND quality of life AND adherence to therapy”, “epilepsy AND quality of life AND retention on therapy”, “epilepsy AND adherence to therapy”, “compliance AND epilepsy AND quality of life”, “adherence to therapy AND retention on therapy AND epilepsy”, “nonadherence to therapy AND epilepsy AND quality of life”. After the selection procedure, 22 scientific publications were included in the review.Results. Factors that have a negative impact on adherence to therapy have been identified (comorbid cognitive impairment, the combination of lack of control over seizures and the presence of adverse events after drug administration, depression and anxiety, the need to change the lifestyle for taking the drug, concern about the potential negative consequences of taking the drug, recent uncontrolled seizures, lack of professional implementation, high frequency of taking the drug, problems with doctor-patient relationship, insufficient social support), and factors that have a positive impact (emotional support from the doctor, establishing doctor-patient partnership).Conclusion. There is a relationship between the patient's quality of life and adherence to therapy. Patient adherence to therapy is important for the effectiveness of epilepsy treatment and, along with the severity of epilepsy, is a significant factor affecting the quality of patients’ life during epilepsy. An opportunity for long-term retention on anticonvulsant therapy also has a cross-correlation with quality of life.
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