Своевременная диагностика паразитарных заболеваний опорно-двигательного аппарата представляет определенные сложности, обусловленные редкостью данной пат ологии. В статье представлено клиническое наблюдение-случай дирофиляриоза влагалища разгибателя пальца кисти у 49-летней женщины, госпитализированной с диагнозом «гигрома тыльной поверхности кисти». правильный диагноз заболевания был поставлен только после извлечения паразита во время операции. Обсуждены проблемы дифференциальной диагностики данного заболевания и гигромы тыла кисти. Для уточнения диагноза предложено использовать предоперационное узИ мягких тканей кисти.
The review presents the data on clinical diagnostic value of studying one of the components of urinary proteome - macrophage chemotactic protein -1 (MCP-1). Along with the general characteristics of MCP-1, there are given the data on changes in its concentration regarding various diseases of the urinary system. It was shown that for various diseases and research conditions, the concentration of MCP-1 can be an important diagnostic criterion in assessing inflammatory, metabolic, fibrotic and other renal lesions.
Objective: A comparative analysis of C-reactive protein (CRP) and procalcitonin concentration in blood serum and seminal plasma of healthy men and men with reduced concentration of sperm cells.Methods: 73 fertile men were examined. The experimental group included 36 patients with a reduced fertility; the comparison group (control) included 37 men with normal indicators of ejaculate composition. The concentrations of CRP and procalcitonin were determined by the method of enzyme-linked immunosorbent assay.Results: Differences in level of CRP between blood serum and seminal plasma in experimental and control groups occurred to be statistically significant in both groups. There was no correlation between these parameters. The concentration of procalcitonin was almost ten times higher in the seminal plasma than in the blood serum. In the experimen‑ tal group, it was significantly higher in ejaculate than in the comparison group. The concentration of CRP and procalcitonin did not correlate neither with the ejaculate volume nor with concentration or amount of sperm cells in it.Conclusions: The levels of CRP and procalcitonin in seminal plasma can indicate the fertility status of the ejaculate.
Introduction. Drinking water is a necessary element of life support of the population. Many studies conducted around the world have established a relationship between the quality of drinking water and public health. On the basis of the Perm State Medical University studies were conducted to assess the effects of oxygen-enriched drinking water on human respiratory, cardiovascular and nervous systems as well as serum erythropoietin (EPO) levels. The objects of study were 32 volunteers (7 men and 25 women) aged 18 to 28. The purpose of the research was to study the effect of oxygen-enriched drinking water on the basic physiological systems of the human body and serum EPO levels of healthy volunteers. Methods. We applied the following research methods: physiological methods were used thrice (on the first, tenth and twenty-first days) to test the cardiovascular (heart rate, SBP, DBP, Kerdo index, Harvard step test), respiratory (BH, JELL, JEL, Stange and Gencha tests) and nervous (Anfimov test, SAN test, ShAS test) systems; laboratory tests of serum EPO levels in venous blood of the volunteers; and statistical methods (statistical processing was performed using Microsoft Office Excel 2007 and STATISTICA V. 7 software package (StatSoft Inc., USA). Results. The use of oxygenated water helps increase functional and reserve capabilities of the basic physiological systems of the body and improve tissue oxygenation.
The study of the protein composition of the ejaculate is devoted to a significantly smaller number of studies than the characterization of the cellular composition of sperm and the characterization of spermatozoa. Objective: to investigate the concentration of procalcitonin (PCT) in seminal plasma and serum in normal conditions and with oligozoospermia. Materials and methods. 88 men were examined (the main group - 40 men with oligozoostantenospermia, the comparison group - 48 men with a normal concentration of spermatozoa). Results and discussion. The concentration of PCT in seminal plasma in the examined patients (n = 88) was almost 10 times higher than its serum content and amounted to 0.349 ± 0.370 ng/ml versus 0.037 ± 0.027 ng/ml (p0.000001). In patients with oligozoospermia the contents of the PC has exceeded the value of the comparison group (p = 0,0095). Serum PCT concentrations in blood serum did not differ between groups (p = 0.605). There were no statistically significant correlations between the level of PCT and other indicators of sperm (sperm concentration, their total content and volume of ejaculate). Summary. The content of PCT in seminal plasma does not depend on its level in blood serum. A higher content of PCT in the ejaculate compared to serum indicates its local production in the reproductive system. The increased procalcitonin level in seminal plasma may indicate decreased fertility of the ejaculate.
The article describes the current understanding of the takotsubo syndrome concerning the issues of pathogenesis, differential diagnosis with acute coronary syndrome and strategy of management. There is presented our own clinical observation of a patient with an atypical form of cardiac dysfunction and myocardial geometry.
The determination of the concentration of procalcitonin (PCT) in blood serum and other biological fluids is used for the diagnosis and monitoring of the course of sepsis and the syndrome of a systemic inflammatory reaction. This review summarizes the data on the diagnostic value of the definition of procalcitonin in the practice of urologists and andrologists. The content of procalcitonin in such biological fluids as urine, seminal plasma is almost 10 times higher than the level of this protein in blood serum: this phenomenon is manifested in physiological conditions and in pathological processes. The relationship of clinical and laboratory indicators of inflammation with the severity of urosepsis was analyzed. Elevated serum procalcitonin levels are considered as a predictor of septic shock in patients with urolithiasis, and determine the management tactics of patients with urinary tract obstruction. The marker function of this protein was studied in inflammation in the renal parenchyma, in malignant neoplasms of the kidneys, bladder, ureter, prostate and testis; in the diagnosis of testicular torsion and orchiepididymitis. The article describes the regular changes in the level of urinary procalcitonin depending on the severity of vesicoureteral reflux, the severity of the manifestations of the inflammatory reaction. There were significant differences in the concentration of procalcitonin in seminal plasma between the groups of men with reduced and normal ejaculate fertility.
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