П о данным Всемирной организации здравоохранения (ВОЗ), продолжают появляться новые формы вирусных заболеваний, что служит вызовом для здравоохранения. За последние 20 лет было зафиксировано несколько вирусных эпидемий, обусловленных SARS-CoV (Severe acute respiratory syndrome related coronavirus-тяжелый острый респираторный синдром, обусловленный коронавирусом) в 2002-2003 гг., вирусом гриппа H1N1 в 2009 г. и коронавирусом ближневосточного респираторного синдрома (MERS-CoV) в 2012 г. Новый коронавирус тяжелого острого респираторного синдрома слу-Применение режима адаптивной поддерживающей вентиляции легких у ребенка с коронавирусной пневмонией на фоне сахарного диабета
The Kawasaki disease is the acute vasculitis specific to the childhood that affects the medium-sized arteries and causes the coronary aneurysms in about 25% of the patients untreated. This disease is one of the causes of the heart diseases acquired in the children in the economically developed countries. The cause of the Kawasaki disease remains unknown. The Article is based on the current guidelines and clinical case, with special focus on the necessity of the early diagnosis and proper treatment, since only early diagnosis and timely treatment of the patients with this disease prevent the damage of the coronary arteries.
We examined 54 patients with acute myocardial infarction who were admitted to the clinic during the first 6-10 hours after the onset of the pain attack. There were 31 men and 23 women. 7 patients were aged 30 to 50 years, 35 patients were aged 51 to 70 years, 12 patients were older than 70 years. According to ECG data, the focus of necrosis in all patients was localized in the anteroposterior region. The results of these patients without atrioventricular conduction abnormalities and acute postinfarction aneurysms of the left ventricle are presented in the article.
Objective. The study of the etiological structure, properties of pathogens of the Vinnytsia National Medical University named after E. Pirogova, respiratory process in newborns who have underwent artificial mechanical lung ventilation (MLV) and their resistance to antibacterial agents is especially relevant in modern conditions, expands the search for new approaches to pathogens, improves treatment and reduces mortality from this pathology.
The purpose of the study - to determine the etiological structure, sensitivity to antibiotics of the leading pathogens of the infectious process of the respiratory system in newborns who were on mechanical ventilation.
Materials and methods. In total, the species composition of the leading microorganisms that colonized the airways of 180 newborns treated in the Neonatal Intensive Care Unit (VAITN) of Vinnytsia Regional Children’s Clinical Hospital (VRCCH) was studied in 2020. A total of 285 isolates of microorganisms were isolated. 62 patients who underwent mechanical ventilation were involved in a prospective microbiological study, 86 clinical strains of microorganisms were isolated. The susceptibility of microorganisms to 30 antibacterial agents was determined according to the generally accepted method (order of the Ministry of Health of Ukraine №167; recommendations). Research results. The etiological significance of opportunistic pathogens (Enterobacter cloacae - 29%, Staphylococcus aureus - 24.4%, Pseudomonas aeruginosa - 18.6%, Candida albicans) was proved in patients who were on mechanical ventilation in VAITN VRCCH in 2020 for pneumonia. Clinical strains of S. aureus are sensitive to vancomycin, oxacillin and clindamycin.
Conclusions. Pathogens of the respiratory process in newborns who have been on mechanical ventilation, are resistant to a number of antibiotic drugs (cefepime, gentamicin amikacin, piperacillin).
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