Several Zn (II) and Al (III) phthalocyanines bearing eight or sixteen positive charges on substituents of different structure have been prepared. Synthesized polycationic phthalocyanines have been studied in aqueous and alcoholic media by UV-vis spectroscopy and tested for their efficacy in singlet oxygen photosensitization. It has been found that a minor structural modification at the periphery of the photosensitizer allows control over its key features such as singlet oxygen generation due to specific intermolecular interactions in solution. The efficacy of polycationic phthalocyanines to sensitize tryptophan photobleaching in aqueous media and inactivation of bacteria in sewage water is also structure-dependent. Among the complexes studied, two dyes - zinc octakis(pyridiniomethyl)- and octakis[ N -(2-hydroxyethyl)- N , N -dimethylammoniomethyl]substituted phthalocyanines - are the best sensitizers and have high potential for photodynamic applications.
A new method of preparation and the properties (solubility, aggregation, spectralluminescent properties, singlet oxygen and photobleaching quantum yields) of non-metal 2,3,9,10,16,17,23,24-octacarboxyphthalocyanine are reported. The influence of ionization state on photophysicochemical properties of this dye is also presented.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.