The aim of the study was to reveal a relationship between gustatory sensitivity to phenylthiocarbamide (PTC) and thyroid disease. The distribution of PTC sensitivity was studied in 198 healthy individuals, 100 patients with autoimmune thyroiditis (AIT), 139 patients with nodular euthyroid goiter, and 100 patients operated on for thyroid cancer. There was a statistically significant decrease in the number of PTC-resistant male and females patients in the thyroid cancer group and an increase in the proportion of PTC-resistant male patients in the AIT and nodular euthyroid goiter groups.

Objective: to develop a method of glossectomy with single-staged glossoplasty in cancer of the mucous membrane of the front one-third part of the tongue. Material. The work is based on the results of surgery of five patients with localization of cancer on the front one-third of the tongue. An up-to-date method of glossectomy of the front one-third of the tongue has been developed. The post-resection defect is eliminated with musculomucosal grafts from the tongue remains with restoration of the volume symmetry of neotongue. Conclusion. The application of the tongue tissues for plastic replacement of the defect minimizes traumatism of the surgery. The preservation of innervation and restoration of the structure ensure good functional effect of the glossoplasty method.