університет». Україна 2 ДУ «Інститут патології хребта та суглобів ім. проф. М. І. Ситенка НАМН України», Харків 3 Національний технічний університет «Харківський політехнічний інститут». Україна
Summary. The use of materials based on bioglass and glass ceramics to replace bone lesions is a promising direction for the treatment of bone defects caused by traumas and tumor-like diseases. Objective. To analyze the results of ASZ-5 and FAR 5 bioglass application to replace long bone defects of traumatic and destructive origin. Materials and methods: the analysis of outcomes of 37 patients treated at the Orthopedics department of Andrew Novak Transcarpathian Regional Clinical Hospital from 2018 to 2020. To be included into the study, the patients should have bone defects of traumatic or destructive origin. The patients were divided into three groups. Surgical treatment of these patients included osteosynthesis and plastics of bone defects with ASZ-3 or FAR 5 bioglass. Results. To assess the results, we studied the outcomes of the 37 patients using a rating scale. The observation period covered 1 – 1.5 years after the surgery.43.24% patients demonstrated good results, 51.35% - satisfactory. The results of two patients (5.41%) were poor. Conclusions. The differentiated approach to the type of an implant to fill long bone defects of traumatic and tumor origin shall consider its mechanical, osteoinductive and osteoconductive properties. In turn, it improves the results of treatment by stimulating a bone’s reparative osteogenesis, and assisting its function.
Робота присвячена вивченню впливу методу інтервального гіпоксичного тренування (ІГТ) на фізичну активність пацієнтів та показники кісткового метаболізму при переломах вертлюгової ділянки стегнової кістки у хворих з тиреотоксикозом та без. Результати дослідження основані на клінічному спостереженні 15 хворих з переломами вертлюгової ділянки стегнової кістки. Отримані дані свідчать про позитивний вплив ІГТ на фізичну активність пацієнтів після оперативного лікування переломів вертлюгової ділянки стегнової кістки та на збільшення рівня показників активності кісткового метаболізму, що особливо виражено у хворих з тиреотоксикозом Ключові слова: інтервальне гіпоксичне тренування, фізична активність, кістковий метаболізм, тиреотоксикоз The method of interval hypoxic training (IHT) is used to increase physical endurance of athletes and for treatment of certain systemic diseases, due to the ability of IHT affect metabolism, homeostasis and the immune system. The aims of the article are improving the results of treatment and rehabilitation of patients with fractures of the trochanteric area of the femur by the method of interval hypoxic training and study its influence on bone metabolism. Materials and methods. 17 patients who were hospitalized in the clinic of general surgery UzhNU with fractures of the trochanteric area of the femur are examined in the period from 2012 to 2015. The first group consisted of 6 patients who from day-patient treatment is conducted IHT by gas mixture of 12 % oxygen. The second group consisted of 4 patients with thyrotoxicosis who are also receiving IHT by gas mixture of 12 % oxygen. The control group consisted of 7 patients with fractures of the trochanteric area of the femur who refused from IHT. Results and its discussion. The best physical activity is observed in the first group. Starting physical activity is the lowest in the second group, but its development is faster. Slowly increase the duration of physical activity compared with the first two groups is observed in the control group. In the control study after 1 month it is noted that calcium level increased in all three groups. Increase in the second group is biggest. The level of phosphorus decreased in the first and the control group and increased in the second group. The levels of osteocalcin and alkaline phosphatase increased. Rates were higher and increase was substantial in the first two groups in comparison with the control group. Conclusions. • Intensive growth of length of one-time physical activity most notably in patients with thyrotoxicosis is observed in patients who are receiving IHT. • Improvement of the activity of bone metabolism is observed in patients after IHT