We demonstrate that charged particles in a sufficiently intense standing wave are compressed toward, and oscillate synchronously at, the antinodes of the electric field. We call this unusual behavior anomalous radiative trapping (ART). We show using dipole pulses, which offer a path to increased laser intensity, that ART opens up new possibilities for the generation of radiation and particle beams, both of which are high energy, directed, and collimated. ART also provides a mechanism for particle control in high-intensity quantum-electrodynamics experiments.

Marklund, M., Sergeev, A. (2011) Ultrarelativistic nanoplasmonics as a route towards extreme-intensity attosecond pulses.Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, 84(4) The generation of ultrastrong attosecond pulses through laser-plasma interactions offers the opportunity to surpass the intensity of any known laboratory radiation source, giving rise to new experimental possibilities, such as quantum electrodynamical tests and matter probing at extremely short scales. Here we demonstrate that a laser irradiated plasma surface can act as an efficient converter from the femto-to the attosecond range, giving a dramatic rise in pulse intensity. Although seemingly similar schemes have been described in the literature, the present setup differs significantly from the previous attempts. We present a model describing the nonlinear process of relativistic laser-plasma interaction. This model, which is applicable to a multitude of phenomena, is shown to be in excellent agreement with particle-in-cell simulations. The model makes it possible to determine a parameter region where the energy conversion from the femto-to the attosecond regime is maximal. Based on the study we propose a concept of laser pulse interaction with a target having a groove-shaped surface, which opens up the potential to exceed an intensity level of 10 26 W/cm 2 and observe effects due to nonlinear quantum electrodynamics with upcoming laser sources.

560 TW peak power has been achieved experimentally using a Cr:forsterite master oscillator at 1250 nm, a stretcher, three optical parametrical amplifiers based on KD*P crystals providing 38 J energy in the chirped pulse at 910 nm central wavelength, and a vacuum compressor providing 43 fs pulse duration. To our knowledge, it is a world-record OPCPA system and one of the five most powerful laser systems currently available.

Possible nonlinear effects in electron-cyclotron plasma production and heating by microwave radiation are analyzed. They include nonlinear regimes of electron acceleration in strong microwave fields under cyclotron resonance conditions, nonstationary regimes of microwave beam self-focusing, and some parametric processes. Presented results may be of importance for predictions of plasma response to electron-cyclotron resonance (ECR) heating or preionization by powerful radiation.

OCT is promising to become a new diagnosing method of laryngeal carcinoma and a tool for laser treatment monitoring.

Mechanisms of mitochondrial dysfunction in sepsis are being extensively studied in recent years. During our study, concentrations of microbial phenolic acids and mitochondrial metabolites (succinic, α-ketoglutaric, fumaric, itaconic acids) as indicators of sepsis and mitochondrial dysfunction, respectively, are measured by gas chromatography–mass spectrometry (GC–MS) in the blood of critically ill patients at the early and late stages of documented sepsis. The increase in levels of some phenylcarboxylic (phenyllactic (PhLA), p-hydroxyphenylacetic (p-HPhAA), p-hydroxyphenyllactic (p-HPhAA)) acids (PhCAs), simultaneously with a rise in levels of mitochondrial dicarboxylic acids, are mainly detected during the late stage of sepsis, especially succinic acid (up to 100–1000 µM). Itaconic acid is found in low concentrations (0.5–2.3 µM) only at early-stage sepsis. PhCAs in vitro inhibits succinate dehydrogenase (SDH) in isolated mitochondria but, unlike itaconic acid which acts as a competitive inhibitor of SDH, microbial metabolites most likely act on the ubiquinone binding site of the respiratory chain. A close correlation of the level of succinic acid in serum and sepsis-induced organ dysfunction is revealed, moreover the most significant correlation is observed at high concentrations of phenolic microbial metabolites (PhCAs) in late-stage sepsis. These data indicate the promise of such an approach for early detection, monitoring the progression of organ dysfunction and predicting the risk of non-survival in sepsis.

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