Objective. To perform comparative analysis of osseointegration of bioceramic alumina-based granules, hydroxyapatitebased granules, and granules of deproteinized bone tissue. Material and Methods. The experiment was conducted on 52 adult male Kyoto-Wistar laboratory rats weighing 350 to 520 g. Animals were divided into five matched groups, which differed only in the type of implanted material. Granules were implanted in lumbar vertebral bodies and in distal right femur of each laboratory animal. Two months after surgery animals were euthanized with subsequent tissue sampling for morphological studies. Results. Examination of specimens from groups with implantation of alumina granules revealed the formed trabecular bone with evidence for remodeling. Bone tissue filled the space between granules fitting closely to their surfaces. There was no connective tissue capsule on the border between the bone tissue and alumina granules. Conclusion. Bioceramic alumina-based granules in the form of cylinders with a through inner channel have high strength surpassing that of analogs and ability for osseointegration close to that of hydroxyapatite and deproteinized bone granules.
Целью работы является обзор некоторых характеристик материалов стоматологических имплантатов и анализ перспектив их использования в современной медицине.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.