Ruutu, J. P.; Hakonen, P. J.; Babkin, A. V.; Parshin, A. Ya.; Penttilä, J. S. ; Saramäki, J. P.; Tvalashvili, G. Facet growth of 4He crystals at mK temperatures

We have investigated creation of 4 He crystals from the superfluid phase at the temperature range 2 mK -1.0 K. Statistical nucleation-event distributions in overpressure were found to be broad, asymmetric, and temperature independent below 100 mK. Our statistical analysis agrees with a theoretical model suggesting that solid formation is driven by macroscopical quantum-mechanical fluctuations from a seed preexisting in a cavity on the wall. [S0031-9007(96)

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Background Ultralow temperature cyroablation (ULTC) is designed to create focal, linear, and circumferential lesions. The aim of this study was to assess the safety, efficacy, and durability of atrial and ventricular ULTC lesions in preclinical large animal models. Methods and Results The ULTC system uses nitrogen near its liquid‐vapor critical point to cool 11‐cm ablation catheters. The catheter can be shaped to specific anatomies using pre‐shaped stylets. ULTC was used in 11 swine and four sheep to create atrial (pulmonary vein isolation and linear ablation) and ventricular lesions. Acute and 90‐day success were evaluated by intracardiac mapping and histologic examination. Cryoadherence was observed during all ULTC applications, ensuring catheter stability at target locations. Local electrograms were completely eliminated immediately after the first single‐shot ULTC application in 49 of 53 (92.5%) atrial and in 31 of 32 (96.9%) ventricular applications. Lesion depth as measured on histology preparations was 1.96 ± 0.8 mm in atrial and 5.61 ± 2.2 mm in ventricular lesions. In all animals, voltage maps and histology demonstrated transmural and durable lesions without gaps, surrounded by intact collagen fibers without injury to surrounding tissues. Transient coronary spasm could be provoked with endocardial ULTC in the left ventricle in close proximity to a coronary artery. Conclusions ULTC created effective and efficient atrial and ventricular lesions in vivo without procedural complications in two large animal models. ULTC lesions were transmural, contiguous, and durable over 3 months.

The growth anisotropy of different facets has been measured in 3He crystals at 0.55 mK using a low-temperature Fabry-Pérot interferometer and high-resolution pressure measurements. The observed linear dependence of the growth velocity on the driving force shows that facets grow due to the presence of dislocations. The values of the obtained step energies suggest that 3He has stronger coupling of the liquid-solid interface to the lattice than has been expected. The dependence of the step energy versus the step height is consistent with a quartic power law pointing out that the step-step interactions are of elastic origin.