The aim of the study was to evaluate the effect of combined use of Cytoflavin and cognitive therapy on the dynamics of psychosomatic status and effectiveness of the treatment of generalized periodontitis in elderly patients. The results of treatment of 103 patients aged 60 and older were analyzed. All patients received standard therapy for 10-14 days depending on the severity of the process. In addition, the patients of the main group (51 patients) received Cytoflavin: 2 tabs. 2 times a day with an interval between doses of 8-10 hours for 25 days, and cognitive therapy aimed at training alternative realistic way of life perception. Treatment results were monitored by PMA, Russell periodontal index (PI), Green-Vermillion hygienic index. Psychosomatic dynamics was assessed by means of Spielberger anxiety scale and SUN" methods of before and after a month of treatment. The inclusion in the treatment regimen of Cytoflavin and cognitive therapy had a positive impact: reduction of PMA by 61.8%, PI by 45.3% and Green-Vermillion index by 39.8%. The psychosomatic tests proved anxiety level decrease by 28.7% in terms of "reactive" anxiety and 31.5% in terms of "personal" anxiety, emotional status (21.2%), activity (21.7%) and mood (21.8%) improvement.
25В опубликованном докладе Министерства труда «О результатах мониторинга социально-экономического положения граждан пожилого возраста» (2014) приводят-ся данные численности пожилых людей (женщин стар-ше 55 лет и мужчин старше 60 лет) в России на 1 января 2013 г. -33,1 млн человек (23,1% населения страны), и Первый центральный научно-исследовательский институт кораблестроения и вооружения ВМФ РФ Цель -изучение эффективности включения в схемы паллиативной помощи пациентам пожилого и старческого возраста с раком прямой кишки и молочной железы III-IV стадии препарата цитофлавин в сочетании с индивидуальной когни-тивной психотерапией. Материал и методы. Проведен анализ терапии 175 больных старше 61 года раком прямой кишки и молочной железы III-IV стадии. Все пациенты получали лечение в рамках Приказа №187н МЗ РФ и были разделены на 2 группы: в 1-ю включили 70 пациентов, получивших помимо основного лечения индивидуальную когнитивную психо-терапию и препарат цитофлавин по 2 таблетки 2 раза в сутки в течение 25 дней, во 2-ю (105 пациентов) были включены па-циенты, получившие стандартное паллиативное лечение. Эффективность лечения оценивали по состоянию качества жиз-ни пациентов методом интервьюирования с помощью русской версии опросника Европейской организации по изучению и лечению рака EORTC QLQ-C30 (версия 3). Результаты. Назначение цитофлавина на фоне проведения индивидуальной когнитивной психотерапии в комплексе паллиативной помощи повысило качество жизни пациентов, что проявлялось в до-стоверном снижении показателей усталости (p<0,01), болевого синдрома (p<0,01) и бессонницы (p<0,05) и улучшении по-казателя аппетита (p<0,05); достоверным повышении показателей функциональной шкалы: физических функций (p<0,01), когнитивной функции (p<0,05), ролевой и эмоциональной функции (p<0,05), социальной функции (p<0,05) и улучшение по шкале общего статуса. Заключение. Полученные данные позволяют рекомендовать включение цитофлавина на фоне индивидуальной когнитивной психотерапии в схемы паллиативной помощи онкологическим больным.Ключевые слова: паллиативная помощь, пожилой и старческий возраст, рак прямой кишки, рак молочной железы, каче-ство жизни, цитофлавин.
The study aimed to identify possible environmental risk factors for breast cancer among women in Gaza Strip and conducted in 2010. A case-control study design was used with face to face interviews by structured questionnaire with breast cancer patient women as well as healthy women. Statistical Package of Social Science (SPSS) was used to analyze the collected data. The study population was 288 women, 144 were women with breast cancer (cases) and 144 were healthy women (controls) with response rate 100% for cases as well as controls. The study was carried out in the two main hospitals in Gaza Strip (El-Shifa and European Gaza) and on cases who had a regular follow up in each hospital, while controls have been chosen from women who had no history of breast cancer by mammogram or by self-examination. In this study the main statistically signifi cant risk factors were; marital status, educational status, physical trauma on breast, medication for infertility treatment, eating red meat 500g or more weekly, eating canned food, eating chicken skin, eating raw and cooked vegetables, using oils with saturated fats in cooking, living in or beside a farm, dealing with crops with naked hands, working in a farm during pesticides application or during 24 hours of pesticides application, cleaning pesticides' equipment, living with people working in a farm or a agricultural fi eld, and application of pesticides personally. In contrary, no statistically signifi cant differences were found between cases and controls in relation to area of residency, exposure to X-ray in the past, having radiation therapy, getting contraceptive pills, using hair dyes, using anti-deodorant underarm, using facial cosmetics, using hair removal ointment, washing vegetables and fruits, buying and transporting pesticides, and wearing protective tools during pesticides mixing and application.
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