Hydrogen polysulfide (H2Sn) has attracted increasing attention due to the fact that it is actually the key signaling molecule rather than hydrogen sulfide (H2S). Therefore, developing a sensitive and accurate assay to investigate the biosynthetic pathways of H2Sn is of physiological and pathological significance. In this work, based on the commonly used two-photon fluorophore, 1,8-naphthalimide, a new probe, NRT-HP, has been designed and synthesized that displayed both one- and two-photon ratiometric fluorescence changes toward H2Sn via H2Sn-mediated benzodithiolone formation. NRT-HP exhibits excellent pH stability, high selectivity and low detection limit (0.1 μM) in aqueous media. Furthermore, two-photon fluorescence microscopy experiments have demonstrated that NRT-HP could be used for the H2Sn detection in live cells as well as tissue slices.
A merocyanine-based highly selective colorimetric and ratiometric fluorescent probe is described for Cys detection in water and diluted deproteinized human serum. Upon reaction with Cys in aqueous buffer solution, the probe showed a dramatic color change from faint yellow to pink and remarkable ratiometric fluorescence enhancement signals were also observed, which are ascribed to an intramolecular charge transfer (ICT) process. This strategy was based on modulating the merocyanine π-electron system by conjugation and removal of the acrylate group to release the chromophore group, resulting in a specific colorimetry and fluorescence response. The probe has low cytotoxicity and good cell permeability. It is readily employed for assessing the change of the intracellular Cys level.
Four dinuclear lanthanide mesocates were fabricated through a spontaneous self‐assembly method, and the formation of these complexes was well studied by their absorption and emission spectra. These stable complexes were also found to exhibit superior performance in catalyzing the coupling reaction between epoxides and CO2 with excellent recyclability. Moreover, the catalysts could be prepared on large scale. Moreover, the Yb and Lu complexes featured emissions in the near‐infrared and visible regions, respectively, and their intensities and lifetimes could be used for identification purposes. Thus, this new approach can be used to construct promising lanthanide complexes as efficient catalysts and it identifies the possibility to better study a catalytic reaction with a luminescent catalyst.
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