This article demonstrates the first cross coupling of benzyl ether with Grignard reagents via Ni-catalyzed benzylic sp3 C−O activation with high efficiency and excellent chemoselectivity. Benzylic sp3 C−O and aryl sp2 C−O were differentiated, controlled by ligands.

Aryl C-O and C-F can be transformed into C-Me via Ni-catalyzed coupling with MeMgBr under mild conditions.

No abstract

Di-or triarylmethanes are synthesized from benzyl ethers and benzene or methyl-substituted benzenes by Friedel-Crafts reaction. Thiophene is also useful for this transformation. -(WANG, B.-Q.; XIANG, S.-K.; SUN, Z.-P.; GUAN, B.-T.; HU, P.; ZHAO*, K.-Q.; SHI, Z.-J.; Tetrahedron Lett. 49 (2008) 27, 4310-4312; Coll. Chem. Mater. Sci., Sichuan Norm. Univ., Chengdu, Sichuan 610066, Peop. Rep. China; Eng.) -Mais 41-095

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.