ABSTRACT:In this study, we used citric acid (CA) as a crosslinking agent, mixed with biopolymer molecular chitosan, to perform a pad-dry-cure treatment on woolen fabrics to study its antimicrobial effects and physical properties with the help of IR spectroscopy, electron microscopy, and differential thermal analysis. From the experimental results, we learned that CA did not crosslink with the woolen fibers if the woolen fabrics were not oxidized by potassium permanganate and that after oxidization, CA produced esterification with the OOH group of the wool and chitosan and transamidation with theONH 2 group of the wool to form a crosslink. The surface crosslinks of the oxidized woolen fibers were relatively coarse, which is undesirable for shrink-proofing and yet beneficial for the antimicrobial and antiseptic effects of the woolen fabrics. It had a negative effect on the fabric softness, yellowness, stretching resistance, and elongation percentage.
BackgroundRed blood cell distribution width (RDW) to albumin ratio (RAR) is associated with poor prognosis in diabetic comorbidities and cancer. However, the association between RAR and prognosis in patients with sepsis remains unclear, which was investigated in this study.MethodsWe conducted a retrospective cohort study based on the Medical Information Mart for Intensive Care (MIMIC) IV version 2.0 database. The primary outcome of this study was 28-day mortality. Secondary outcomes included 90-day mortality, in-hospital mortality, length of hospital stay, and length of intensive care unit (ICU) stay. Multivariate regression analysis and subgroup analysis were performed to investigate the association between RAR and prognosis in patients with sepsis.ResultsA total of 14,639 participants were included in this study. The mean age of the participants was 65.2 ± 16.3 years and the mean RAR was 5.5 ± 1.9 % /g/dl. For 28-day mortality, after adjusting for covariates, HRs [95% confidence intervals (CIs)] for tertiles 2 (4.4–5.8) and 3 (RAR > 5.8) were 1.33 (1.20, 1.46) and 1.98 (1.79, 2.19), respectively. Similar results were observed for 90-day mortality and in-hospital mortality. According to Kaplan-Meier curve analysis, the higher RAR group had higher 28-day mortality and 90-day mortality.ConclusionOur study shows that RAR is significantly associated with poor clinical prognosis in sepsis. The higher the RAR, the higher the 28-day, 90-day, and in-hospital mortality.
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