Introduction: Cervical cancer is the second most common cancer affecting women in the world. Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. The aim of this study was to evaluate the awareness about HPV, risk perception, cervical cancer, and HPV vaccines. Methodology: The sample of this descriptive cross-sectional study consisted of 396 undergraduate university students from Turkey. Sociodemographic characteristics, reproductive health, knowledge about HPV, and HPV vaccination were questioned. Results: The percentage of university students with an active sexual life was 10.6%. The knowledge level of families about HPV, and HPV vaccination were not adequate. The awareness of the fact that HPV was a cause of cervical cancer in women and penile cancer in men tended to increase with the increase in the educational level of parents. Those who knew about HPV vaccines were predominantly females. Conclusions: The results of this study demonstrated that more active education is needed to decrease HPV infections among undergraduate students. Increasing awareness of HPV makes it easier to develop positive behaviors in fighting against it. In order to increase the contribution of young people to educational activities for the community, information about HPV and HPV vaccines should first be included in training programs at universities. To support the development of effective and high-quality public health interventions, young people should be educated so that obstacles to HPV vaccination in various cultural groups can be eliminated. Our findings suggest that awareness about HPV, cervical cancer, and HPV vaccines should be increased.
Objective: The aim of this study was to investigate the potentially deleterious effect of in vivo high-fructose feeding of rats on ex vivo hemodynamic recovery and infarct size of isolated rat hearts subjected to low-flow ischemia and reperfusion. Methods: After feeding Sprague-Dawley male rats with a high-fructose (n=9), high-glucose (n=9) or a standard diet (n=9) for four weeks, the hearts were extirpated and perfused ex vivo with a Krebs-Henseleit solution for 15 min; thereafter the hearts were subjected to low flow (0.3 ml/min) ischemia during 30 min followed by 60 min reperfusion. Left ventricular developed pressure (LVDP), first derivative of pressure development during the contraction and relaxation phase and heart rate were recorded prior to ischemia and after reperfusion. Infarct area was measured at the end of the reperfusion period. Results: In isolated hearts, subjected to ex vivo low-flow ischemia followed by 60 min reperfusion, the relative myocardial infarct size did not differ between the three groups. Post-ischemic cardiac contractile recovery appeared to be complete in both the high-fructose and high-glucose group at 60 min reperfusion. In contrast, in the control group LVDP and left ventricular relaxation rate were still depressed at the end of 60 minutes of reperfusion. Conclusion: Feeding with a high-fructose diet of rats appears to have a positive effect on the recovery of left ventricular contractile function after low-flow ischemia, in comparison to a standard diet, without a difference in relative myocardial infarct size. Similar results were obtained in the high-glucose fed rats.
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