Exposure
of toxic vapors had a harmful effect on human health.
The solid-phase microextraction (SPME) device has been widely used
because of its great simplicity, high efficiency, and low cost, especially
when used for analysis of gaseous compounds through coupling with
GC-MS. In this work, an on-site SPME-like handy detection device (termed
AIE Handy Pen) was developed by decoration of toxic vapors responsive
AIEgens (TPE-Py, responsive to diethyl chlorophosphite (DCP, nerve
agent) or 1,2-dihydroquinoxaline (DQ2), responsive to amine vapor)
on the SPME fiber by a sol–gel process. Thanks to its unique
solid-state emission characteristics, the AIEgens can be illuminated
upon exposure to gaseous compounds on the fiber, and the fluorescence
of the reacted AIEgens could be easily visualized under UV-illumination.
The detection limit could be as low as 3.4 ppb (for DCP vapors) or
0.2 ppm (for amine vapors) with the minimal detection time of 30 min
(for DCP vapors) or 5 min (for amine vapors). This AIE pen could be
easily expanded by decoration of different kinds of responsive AIEgens
for on-site analysis of various toxic vapors.
Development
of an easy-to-use, low-cost, household device can help
the consumer quickly identify an organophosphorus (OP) residue concentration
level. In this work, we demonstrate a 3D-printed, portable, fluorescent-sensing
platform for smartphone-capable detection of OPs in vegetables. For
development of the proposed device, we utilize the smartphone for
capturing the strong thiol-activated fluorescence, which was produced
by hydrolysis of OPs in the presence of alkali. The thiol-responsive
AIEgen (maleimide-functionalized tetraphenylethylene) was non-emissive
in both solution and the solid state but could be readily lighted
up by the click addition of thiol to its MI pendant. An android application
“Detection” has been developed on the basis of the gray
value to analyze the different concentration levels of OPs in vegetable
samples. The gray value was linearly related with the concentration
of five kinds of organophosphorus residue, ranging from 0 to 20 μg/mL.
It was also applied for determination of OPs residue in the leaves
of cowpea, celery, and Chinese cabbage. Different from acetylcholinesterase
enzyme-based sensors for poor stability under high temperature, the
proposed method was a direct detection method for OPs and can be used
for rapid monitoring of OPs residue concentration levels before LC-MS
analysis.
Development of affordable, simple and effective methods for rapid on-site identification of genetically modified organisms (GMO) is urgent due to public concern for transgenic food.
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