The actual role of 18F-FDG PET/CT in evaluating primary brain lymphoma is still an open issue. Brain lymphoma usually show elevated 18F-FDG uptake, often higher than other brain tumors or inflammatory processes, but the metabolic behavior of this lymphoma is not still understood. Central nervous system lymphoma is a rare non-Hodgkin lymphoma in which malignant (cancer) cells from lymph tissue form in the brain and/or spinal cord (primary CNS) or spread from other parts of the body to the brain and/or spinal cord (secondary CNS).A 55 year-old man presented with headache. Magnetic Resonance Imaging (MRI) revealed a well-enhanced mass lesion in the left frontal lobe. A surgical specimen obtained through left orbito-pterional craniotomy revealed a Diffuse Large B-Cell Lymphoma (DLBCL). 18F FDG PET-CT scan showed multiple hypodensehypermetabolic lesions in brain. Multiple hypodense focal hypermetabolic areas were seen in right frontal lobe, left frontal lobe and left temporal lobe. There was also a subcentimetrichypermetabolic sub-carinal lymph node. The activity was diminished on follow-up PET-CT after 8 courses of chemotherapy. This case indicates that FDG PET-CT scan can aid identify the atypical primary CNS lymphoma for staging workup and can be a useful tool to see treatment response.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.