Background To investigate and assess the correlation between inflammatory markers, such as the preoperative neutrophil-lymphocyte ratio (NLR), and the recurrence of idiopathic granulomatous mastitis (IGM). Methods All patients with IGM who were free of malignancy or inflammatory diseases were included in this retrospective analysis between January 2013 and December 2019. On the basis of the presence or absence of recurrence, the patients were split into two groups. After collecting retrospective data, the relationship between patient characteristics, hematological markers such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), NLR, platelet-lymphocyte ratio (PLR), and white blood cell count (WBC), and their connection with postoperative recurrence were assessed utilizing univariate and multivariate analyses, receiver operating characteristic curves (ROC curves), and logistic regression. Results Recurrences occurred in 40.0% (32/80) of the 80 patients over a median follow-up duration of 35.5 months (22.0-47.8 months). The recurrent group showed higher NLR and CRP than the non-recurrent group (PNLR = .003, PCRP = .02). Neutrophil-lymphocyte ratio and postoperative recurrence were associated (correlation coefficient r = .436, P = .01). The ROC curve’s ideal threshold, which had predictive value for IGM recurrence, was 2.18 (sensitivity: 46.9%; specificity: 14.6%). Conclusion The preoperative NLR is a simple and affordable way to predict IGM relapse, which is important for directing clinical work.
Background
Breast cancer metastasis accounts for only 0.4–2% of all breast cancer cases. Gastric cancer with breast metastases is extremely rare, while mammary and ovarian metastases from the stomach are even more uncommon. Breast metastases might be mistaken for primary cancer due to their uncommon and generic clinical and radiological symptoms, leading to ineffective and debilitating therapy.
Case Presentation:
We present a 43-year-old woman with bilateral multiple metastases from stomach signet-ring cell carcinoma to the breast and ovary, which is the seventh case to our knowledge.
Conclusion
We highlight the epidemiological, diagnostic, therapeutic, and prognostic aspects of this extremely rare disease through our case, which are critical to understand in order to avoid diagnostic errors and subsequent incorrect care.
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