As ite-selective electrochemical … …C of arenes with CO 2 is reported by Youai Qiu and co-workers Research Article (e202214710). Ad irect metal-free,b ase-free,a nd site-selective electrochemical CÀHc arboxylation of arenes by reductive activation using CO 2 as an economic and abundant carboxyl source was developed. Ther obust nature of this strategy is reflected in abroad scope of substrates,excellent atom economy,and unique selectivity.

Enantiopure monohydrosilanes are versatile chiral reagents for alcohol resolution and mechanistic investigation. Herein, we have demonstrated the asymmetric synthesis of monohydrosilanes via an intramolecular hydrosilylation strategy.This protocol is suitable for the synthesis of five-and sixmembered cyclic monohydrosilanes,including aclass of chiral oxasilacycles,w ith excellent diastereo-, regio-, and enantioselectivities.N otably,t he catalyst loading could be reduced to 0.1 mol %which makes this one of the most efficient methods to access chiral monohydrosilanes.M echanistic studies and DFT calculations indicate this Rh-catalyzed intramolecular asymmetric hydrosilylation reaction might proceed via aChalk-Harrod mechanism, and the enantio-determining step was predicted to be oxidative addition of Si À Hb ond.

Herein, a direct, metal-free, and site-selective electrochemical CÀ H carboxylation of arenes by reductive activation using CO 2 as the economic and abundant carboxylic source was reported. The electrocarboxylation was carried out in an operationally simple manner with high chemo-and regioselectivity, setting the stage for the challenging site-selective CÀ H carboxylation of unactivated (hetero)arenes. The robust nature of the electrochemical strategy was reflected by a broad scope of substrates with excellent atom economy and unique selectivity. Notably, the direct and selective CÀ H carboxylation of various challenging arenes worked well in this approach, including electron-deficient naphthalenes, pyridines, simple phenyl derivatives, and substituted quinolines. The method benefits from being externally catalyst-free, metal-free and base-free, which makes it extremely attractive for potential applications.

Herein, a straightforward and efficient route for the construction of dual α,β-C(sp3)–H functionalized cyclic N-aryl amines using a combination of electrocatalysis and iron catalysis is disclosed. This approach is achieved...

Herein, a direct, metal-free, and site-selective electrochemical CÀ H carboxylation of arenes by reductive activation using CO 2 as the economic and abundant carboxylic source was reported. The electrocarboxylation was carried out in an operationally simple manner with high chemo-and regioselectivity, setting the stage for the challenging site-selective CÀ H carboxylation of unactivated (hetero)arenes. The robust nature of the electrochemical strategy was reflected by a broad scope of substrates with excellent atom economy and unique selectivity. Notably, the direct and selective CÀ H carboxylation of various challenging arenes worked well in this approach, including electron-deficient naphthalenes, pyridines, simple phenyl derivatives, and substituted quinolines. The method benefits from being externally catalyst-free, metal-free and base-free, which makes it extremely attractive for potential applications.