Highly stereoselective access to β-glycosyl esters
was disclosed,
employing 1-hydroxybenzotriazole (HOBt) mediated esterification of
glycosyl hemiacetals in the presence of EDCI and 1,4-diazabicyclo[2.2.2]octane
(DABCO). Mechanistic studies indicated a dynamic kinetic acylation
pathway. In addition, a stereoretentive esterification of glycosyl
hemiacetals with tert-butyloxycarbonyl ortho-hexynylbenzoate and DMAP was also reported.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.