Photoacoustic (PA) spectroscopy techniques enable the detection of trace substances. However, lower threshold detection requirements are increasingly common in practical applications. Thus, we propose a systematic geometry topology optimization approach on a PA cell to enhance the intensity of its detection signal. The model of topology optimization and pressure acoustics in the finite element method was exploited to construct a PA cell and then acquire the optimal structure. In the assessment, a thermo-acoustic model was constructed to properly simulate the frequency response over the range of 0–70 kHz and the temperature field distribution. The simulation results revealed that the acoustic gain of the optimized cell was 2.7 and 1.3 times higher than conventional cells near 25 and 52 kHz, respectively. Moreover, the optimized PA cell achieved a lower threshold detection over a wide frequency range. Ultimately, this study paves a new way for designing and optimizing the geometry of multifarious high-sensitivity PA sensors.
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