We study the ferromagnetic properties of spin-1 system, which is considered in the frame of the bond-dilution and random positive or negative anisotropy Blume–Capel model in the effective field theory and a cutting approximation. The investigation of phase diagrams displays some rich properties of the trajectory of tricritical point, reentrant phenomena at low temperatures. Under certain both bond concentrations and random negative anisotropy, there are new transition lines of double tricritical points. So special emphasis is placed on the influence of the bond dilution and random anisotropy on phase diagrams. The magnetizations of the system are also discussed. Some results have not been revealed in previous reports.
Objective:
To analyze and verify the main drug components and targets of "Fuzi-Guizhi" in the treatment of osteoarthritis by using the network pharmacology platform.
Methods:
The integrated pharmacology of "Fuzi-Guizhi" was analyzed by using the platform of integrated pharmacology of traditional Chinese medicine, to explore its mechanism in the treatment of osteoarthritis. By establishing an arthritis model in vitro,the pharmacological effect of "aconite-cassia twigs" on articular cartilage was evaluated and conducted for molecular docking.
Results:
28 candidate active components, 37 compound targets, and 583 osteoarthritis related potential targets were screened, and 10 key target processes were screened in the protein interaction network model. Enrichment analysis showed that the 10 core targets involved 958 GO biologic function items and 76 KEGG signal pathways, which were mainly related to apoptosis and mitochondrial functional metabolism. And "Fuzi-Guizhi" drug-containing serum inhibited the expression of Caspase-3 mRNA and protein in chondrocytes and promoted the synthesis of ATP.
Conclusion:
Our research is preliminary that the mechanism of action of "Fuzi-Guizhi" may inhibit chondrocyte degeneration by resisting mitochondrial apoptosis, and further experimental research is required to determine.
A new type of hyper chaotic oscillator is proposed based on the typical Colpitts chaotic oscillators. The chaotic signal is generated as the excitation signal of the wireless transmission system. Two types of Colpitts chaotic oscillation signals are compared from three aspects. We can find that the hyper chaotic Colpitts oscillation signal has the characteristics of more efficient wireless transmission efficiency compared to the typical Colpitts chaotic oscillation signal. Furthermore, the Complementary Cumulative Distribution Function curves show that the hyper chaotic Colpitts oscillation circuit has a preferable conversion efficiency of the rectifier circuit in the wireless power transmission system. Finally, the detailed chart of conversion efficiency of these circuits has been demonstrated.
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