This work aimed to compare the stress distribution and mechanical properties of our bridge combined fixation system and commonly used metal locking plate screw system by finite element analysis and by using the Zwick/Z100 testing machine. In addition, we also investigated the clinical outcome of our bridge combined fixation system for femoral fractures in 59 patients from June 2005 to January 2013. As a result, the stress distribution in the bone plate and screws of metal locking plate screw system during walking and climbing stairs was significantly lower than that of metal locking plate screw system. No significant difference in the displacement was observed between two systems. The equivalent bending stiffness of bridge combined fixation system was significantly lower than that of metal locking plate screw system. There were no significant differences in the bending strength, yield load, and maximum force between two systems. All the cases were followed up for 12-24 months (average 18 months). The X-ray showed bone callus was formed in most patients after 3 months, and the fracture line was faint and disappeared at 6-9 months postoperatively. No serious complications, such as implant breakage and wound infection, occurred postoperatively. According to self-developed standard for bone healing, clinical outcomes were rated as excellent or good in 55 out of 59 patients (success rate: 93.2%). Therefore, our findings suggest that our bridge combined fixation system may be a promising approach for treatment of long-bone fractures.
Nucleus pulposus cell (NPC) transplantation can be a potential therapeutic approach for intervertebral disc degeneration (IDD). However, low cell viability has restricted the therapeutic capacity of NPCs, and sources of natural NPCs are limited. Bone marrow-derived mesenchymal stem cells (BMSCs) and adipose-derived mesenchymal stem cells (ADSCs) can be differentiated toward NPC-like cells. However, it is unknown whether there are differences in the abilities of these two cell types to differentiate into NPC-like cells, or which cell type exhibits the best differentiation ability. The present study compared the abilities of BMSCs and ADSCs to differentiate toward NPC-like cells with or without a 3D culture system to lay a foundation for stem cell transplantation therapy for IDD. BMSCs were isolated from the rat whole bone marrow cell using the repeated adherent culture method. ADSCs were isolated from rat adipose tissues in the subcutaneous inguinal region using the enzyme digestion method. Cells were identified using flow cytometry. Cell viability was assessed via Cell Counting Kit-8 assays, and reverse transcription-quantitative PCR and western blotting were carried out to evaluate the expression of NPC markers and chondrocyte-specific genes. Glycosaminoglycans (GAGs) and proteoglycans were examined via Alcian blue and safranin O staining, respectively. ADSCs in 3D culture displayed the highest cell proliferative ability, compared with the 2D culture system and BMSC culture. In addition, ADSCs in 3D culture exhibited increased GAG and proteoglycan synthesis than BMSCs. Compared with BMSCs in 3D culture, ADSCs in 3D culture exhibited higher mRNA and protein expression of NPC marker genes (hypoxia-inducible factor 1-α, glucose transporter 1) and chondrocyte-specific genes (Sox-9, aggrecan and type II collagen). The present findings indicated that ADSCs exhibited a better ability to differentiate into NPC-like cells in 3D culture compared with BMSCs, which may be of value for the regeneration of intervertebral discs using cell transplantation therapy.
There are some problems in the process of video intelligent description and analysis of volleyball, such as poor effective information extraction rate and poor dynamic tracking effect. Based on this, combined with long-term and short-term memory network and attention mechanism, this paper designs an intelligent description model of volleyball video based on deep learning algorithm and studies how to improve the extraction rate of volleyball video information through intelligent detection hardware and image recognition technology. This paper first introduces the application of image recognition technology and deep learning algorithm in the intelligent description of volleyball video, then designs the volleyball video and image recognition model based on deep learning algorithm according to the requirements of volleyball video intelligent description, and selects three correlation factors related to the impact indicators of volleyball skills. This study selects three characteristic parameters associated with volleyball video analysis indexes, namely, take-off, bounce, and hand movement, combined with image sensing hardware assisted sensor network to realize real-time monitoring of action state in volleyball video analysis system. The experimental results show that, compared with the current mainstream sports video intelligent analysis and image recognition methods with data analysis as the core, the intelligent volleyball sports video intelligent description and image recognition system based on the integration of deep learning algorithm and sensor hardware assistance has the advantages of good detection effect, high data effectiveness, low cost, and high efficiency of volleyball sports video analysis. It can effectively improve the efficiency of volleyball video intelligent description.
BackgroundWe deeloped a novel technique – fast mobile-window small incision (FMWSI) – a modification of minimally invasive surgery for total hip arthroplasty, which we believe is particularly suited to elderly patients with hip fractures. The present article aimed to introduce this technique and compare the clinical effects between the FMWSI technique and conventional incision (CI) for hip arthroplasty in elderly patients.Material/MethodsThis study included 240 consecutive patients who underwent hip arthroplasty. Half received total hip arthroplasty and half received hemi hip arthroplasty. The 120 patients in each group were further divided into FMWSI and CI groups. The following parameters were compared between the FMWSI and CI groups: length of incision, operation time, bleeding volume, drainage volume, postoperative ambulation time, and Harris score.ResultsCompared with the CI group, the FMWSI group had a significantly shorter incision length, operation time, and postoperative ambulation time, as well as lower bleeding and drainage volumes, irrespective of whether the treatment was total or hemi hip arthroplasty (P<0.05). However, no significant difference was found in the Harris score between the FMWSI and CI groups (P>0.05).ConclusionsThe novel FMWSI technique introduced in this study is a useful method for hip arthroplasty, especially for elderly patients with poor constitutions or tolerance to surgery.
Background: The aim of this study is to assess comparatively the clinical effect of cemented and other biological type of artificial femoral head in the treatment of intertrochanteric fractures of the femur in elder patients.Methods: The clinical data of 121 patients with unstable intertrochanteric fractures treated with hip replacement from July 2017 to December 2018 in our hospital were reviewed.Results: There were 121 patients with unstable intertrochanteric fracture received hip replacement enrolled in this study. Of those patients, 60 patients received bone cement femoral prosthesis (bone cement group), while 61 cases (62 hips) received biological femoral prosthesis (biological group). The results showed that the biological group treated had shorter operation time, less intraoperative bleeding and longer time of complete weight-bearing than the bone cement group (P < 0.05), but there was no significant difference in the time of partial weight-bearing and Harris score of hip joint function between the two groups (P > 0.05). Conclusion: The cemented and biological artificial type of femoral head might lead to satisfactory short-term results in the treatment of intertrochanteric fractures for elder patients. Results showed that the biological group had shorter operation time, less intraoperative bleeding and longer time of complete weight-bearing than the bone cement group. For the unstable intertrochanteric fracture of femur with severe osteoporosis and difficult to maintain stability after fracture reset, biological femoral prosthesis stems might be employed for the treatment of artificial hip replacement according to the shape of the proximal femoral cavity, the quality of bone and the range of fracture coverage, which may promote the recovery of hip joint function and obtain good clinical effect.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.