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Objective Contrast-induced nephropathy (CIN) is a serious complication in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention (PCI). This study aimed to analyze the potential risk factors for CIN in patients undergoing PCI. Methods Patients with ACS who underwent PCI treatment from January 2017 to January 2020 were selected. The patients’ characteristics and medical information were collected and compared. Results A total of 1331 patients undergoing PCI were included. The incidence of CIN was 15.33%. Logistic regression analyses showed that a left ventricular ejection fraction ≤45% (odds ratio [OR] 4.18, 95% confidence interval [CI] 1.10–7.36), serum creatinine levels ≤60 μmol/L (OR 3.03, 95% CI 1.21–5.57), age ≥65 years (OR 2.75, 95% CI 1.32–4.60), log N-terminal pro-B-type natriuretic peptide levels ≥2.5 pg/mL (OR 2.31, 95% CI 1.18–5.13), uric acid levels ≥350 μmol/L (OR 2.29, 95% CI 1.04–5.30), emergency percutaneous intervention (OR 1.35, 95% CI 0.34–3.12), and triglyceride levels ≤1.30 mmol/L (OR 1.10, 95% CI 0.01–2.27) were independent risk factors for CIN in patients who underwent PCI. Conclusions Early prevention is required to reduce the occurrence of CIN in patients who undergo PCI and have risk factors for CIN.

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The kinematics and internal deformation of a failure mass during the flow-like moving off a slope were monitored and quantified with the particle flow method in this study. Two kinds of cases were investigated, noncohesive and cohesive granular slopes. Three different internal friction angles and cohesive strengths were considered to systematically investigate their effect on the kinematics and internal deformation of the failure mass. We analyzed the movement within the failure mass and concluded that the mass moves downwards in an undulating pattern. The slope surface topography changes from a straight line to curved lines with slope breaks in a convex geometry. In addition, dilatation within the failure mass, which deforms internally and heterogeneously, is strongly dependent on its mechanical properties. A larger mass moves downslope, and the mass moves faster and further in the model with lower internal friction and cohesion. The internal friction and cohesion have a positive impact on porosity and two-dimensional (or volumetric in 3D) strain within the failure mass.

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