The objective of this study was to effectively screen out a Lactobacillus strain with excellent adhesion ability and ameliorative effect on the disease symptoms of a murine ulcerative colitis model.
This study investigates whether goserelin can inhibit ovarian cancer proliferation and protect ovarian function from cisplatin (CDDP). We evaluated proliferation and AKT phosphorylation in goserelin-treated ES-2 and SKOV3-ip ovarian cancer cells. Anti-Müllerian hormone (AMH) in human granulosa cells (hGCs) cotreated with goserelin and CDDP was measured by ELISA. Tumour volumes, Ki-67 expression, estrus, follicles, ovarian volumes, and serum AMH were compared in nude mice bearing transplanted tumours treated with goserelin and/or CDDP. Our results showed that goserelin inhibited cellular proliferation and AKT phosphorylation in vitro, and inhibited tumour growth and Ki-67 expression in vivo. Goserelin and CDDP cotreatment decreased the estrus cycles of the nude mice and prolonged estrus duration. Goserelin abrogated the CDDP-induced down-regulation of primary and preantral follicle percentage and ovarian volume. Goserelin increased AMH secretion in vitro and in vivo. In conclusion, goserelin inhibited ovarian cancer proliferation and simultaneously protected ovarian function from CDDP.
The performance of airplane in commercial airline environment is determined by, and therefore an indicator of performance measure of, the thermodynamic properties of airplane. The aim of this study was to establish the use of simulators to determine aircraft accident for a flight of airplanes and evaluate the potential of new airspace structure and airport’s runway. This indicates that there is a possibility of obtaining airplane performance from analysis and verification simulating airplane. As compared with AIRBUS Full Flight Simulator, a multiple aircrafts flight simulator that grouping aircrafts simultaneously take off and land was presented, which is basis on a parallel distributed computing in Open Grid Computing Environment (OGCE), and service oriented architecture (SOA) of software in multiple aircraft simulator, the performance of collaborative flight of multiple aircrafts is evaluated.
In modem manufacturing,the various and complex requirement of industry makes the CNC machine tools more and more automatic and networking.While a remote monitoring and intelligent fault diagnosis system is the basic and indispensable unit for automatic and networking machine tools.This paper is focused on open CNC system,the condition monitoring, and fault diagnosis technology are researched of open CNC system. Integration achieved the CNCmachine tools' status remote monitoring and intelligent fault diagnosis, and detailed analysis of the key technologies for the components of the system. Through effectively integration of the computer technology, Fault Tree Analysis method, or other technologies to enhance the automation, networking and intelligent level of the open CNC system. Keywords: open CNC system; remote monitoring; intelligent fault diagnosis ;Fault Tree Analysis Method;
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