Currently, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been reported in almost all countries globally. No effective therapy has been documented for COVID-19, and the role of convalescent plasma therapy is unknown. In the current study, 6 patients with COVID-19 and respiratory failure received convalescent plasma a median of 21.5 days after viral shedding was first detected, all tested negative for SARS-CoV-2 RNA within 3 days after infusion, and 5 eventually died. In conclusion, convalescent plasma treatment can end SARS-CoV-2 shedding but cannot reduce the mortality rate in critically ill patients with end-stage COVID-19, and treatment should be initiated earlier.
Three specimens with ribbed stainless steel rebar and one specimen with ribbed ordinary steel rebar are tested concerning the strength degradation and energy dissipation of stainless steel reinforced concrete columns. The tests results indicate that the damage of the specimens exhibit ductile failure characteristics, and the reinforced concrete columns with stainless steel rebar damage to a lesser extent, appear good ductility and energy dissipation. The strength degradation of stainless steel reinforced column with high axial compression ratio is quite obvious, and with the increasing of the stirrup ratio of column with stainless steel rebar, the strength of column is enhanced.
Aiming at the problem of serious deformation and failure of the surrounding rock of the main roadways in diabase zone in west wing on-500m leve in Dongbaowei Coal Mine and roof caving occurring several times, the rupture characteristics of roadway roof rock was observed in this paper. And the observation result shows that the rupture of the roof rock of the roadways in diabase zone has obvious zoning characteristics, and the roadway roof rock is divided into three zones: fragmentation zone, fissure zone and intact rock zone. According to this, this paper introduced a new concept of controlling roadway roof subsidence and redesigned the support parameters of the roof of the roadway in diabase zone. The deformation monitoring of the testing roadway roof rock was carried out, and the monitoring result shows that the anchor supporting scheme which was based on the “three zones” of roadway roof could control the roof rock deformation better. This indicates that roadway anchor support design method which is based on the “three zones” of roadway roof is correct and feasible.
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