The intriguing opportunities enabled by the use of living components in biological machines have spurred the development of a variety of muscle‐powered biohybrid robots in recent years. Among them, several generations of tissue‐engineered biohybrid walkers have been established as reliable platforms to study untethered locomotion. However, despite these advances, such technology is not mature yet, and major challenges remain. Herein, steps are taken to address two of them: the lack of systematic design approaches, common to biohybrid robotics in general, and in the case of biohybrid walkers specifically, the lack of maneuverability. A dual‐ring biobot is presented which is computationally designed and selected to exhibit robust forward motion and rotational steering. This dual‐ring biobot consists of two independent muscle actuators and a four‐legged scaffold asymmetric in the fore/aft direction. The integration of multiple muscles within its body architecture, combined with differential electrical stimulation, allows the robot to maneuver. The dual‐ring robot design is then fabricated and experimentally tested, confirming computational predictions and turning abilities. Overall, a design approach based on modeling, simulation, and fabrication exemplified in this versatile robot represents a route to efficiently engineer complex biological machines with adaptive functionalities.
Bioengineering approaches that combine living cellular components with three-dimensional scaffolds to generate motion can be used to develop a new generation of miniature robots. Integrating on-board electronics and remote control in these biological machines will enable various applications across engineering, biology, and medicine. Here, we present hybrid bioelectronic robots equipped with battery-free and microinorganic light-emitting diodes for wireless control and real-time communication. Centimeter-scale walking robots were computationally designed and optimized to host on-board optoelectronics with independent stimulation of multiple optogenetic skeletal muscles, achieving remote command of walking, turning, plowing, and transport functions both at individual and collective levels. This work paves the way toward a class of biohybrid machines able to combine biological actuation and sensing with on-board computing.
PurposeIntelligent manufacturing has attracted extensive attention from national strategy, academic research and enterprises' practices. The purpose of this study is to investigate the influence of intelligent manufacturing on performance in manufacturing firms. Moreover, how intelligent manufacturing technology affects enterprise performance, this study provided a practice that can be replicated by other businesses.Design/methodology/approachThis study uses text mining to collect the intelligence level of Chinese listed companies. It uses quantitative analysis to test the proposed model based on samples of 2,091 manufacturers.FindingsIntelligent manufacturing has positive effect on short-term performance and long-term performance. Intelligent manufacturing can empower firms with ambidextrous capabilities, including exploit capability and explore capability. Exploit capability has positive effects on short-term performance and long-term performance. Explore capability has negative effects on short-term performance, but has positive effects on long-term performance.Originality/valueOn the theoretical side, it enriches the research framework between intelligent manufacturing and enterprise performance. This study explains the preconditions and results of ambidextrous capabilities. Moreover, based on the practice-based view (PBV), this study proposes that technologies can be used as strategies, filling a gap in the existing research on strategic management. On the practical side, how to quantify the intelligent manufacturing level of enterprises provides a certain reference. Also, this study provides an easy to imitate practice that can serve as a model for under-performing enterprises.
Biohybrid Walkers In article number http://doi.wiley.com/10.1002/aisy.202000237, Rashid Bashir, Mattia Gazzola, and co‐workers present a maneuverable dual‐ring biohybrid walker designed and selected through a systematic approach based on modeling, simulation, and fabrication. This dual‐ring biobot consists of two tissue‐engineered muscle ring actuators and a 3D‐printed four‐legged scaffold asymmetric in the fore/aft direction. The integration of two independent muscles on a flexible body, combined with external electrical stimulation, provides the dual‐ring biobot with directional walking and rotational steering abilities.
To solve the inherent safety problem puzzling the coal mining industry, analyzing the characteristic and the application of distributed interactive simulation based on high level architecture (DIS/HLA), a new method is proposed for developing coal mining industry inherent safety distributed interactive simulation adopting HLA technology. Researching the function and structure of the system, a simple coal mining industry inherent safety is modeled with HLA, the FOM and SOM are developed, and the math models are suggested. The results of the instance research show that HLA plays an important role in developing distributed interactive simulation of complicated distributed system and the method is valid to solve the problem puzzling coal mining industry. To the coal mining industry, the conclusions show that the simulation system with HLA plays an important role to identify the source of hazard, to make the measure for accident, and to improve the level of management.
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