2,3-dihydro-1H-inden-1-one derivatives were synthesized by [5+2-2] decarbonylative cycloaddition of 1H-indene-1,2,3-trione and norbornene via rhodium (I) catalyzed direct carbon–carbon bond cleavage. The catalytic system combining [Rh(COD)Cl]2 (5.0 mol%) and rac-BINAP(10 mol%)...
Tanshinlactone has been found in several natural products
and biologically
active compounds. Herein, a new FeCl3-catalyzed strategy
using 1H-indene-1,2,3-triones and alkynes as starting
materials is reported to obtain various tanshinlactone derivatives.
This protocol has the advantages of involving low cost, environmentally
benign catalysts, simple reaction conditions, and a broad range of
substrates.
10-Arylbenzo[
h
]quinolines were synthesized by
cross-coupling of ethyl benzo[
h
]quinoline-10-carboxylate
with arylboronic acids
via
group-directed Ni(0) catalyzation.
The catalytic system combining Ni(COD)
2
(10 mol %) with
PCy
3
(20 mol %) and
t
-BuOK (3 equiv) was
optimal for the above transformations. A series of arylboronic acids
reacted with ethyl benzo[
h
]quinoline-10-carboxylates
for the production of various substituted 10-phenyl[
h
]quinolines in moderate and good yields under optimized reaction
conditions.
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