A new technique for single molecular peptide sequencing is demonstrated by translocation of ssDNA-conjugated-peptide through MspA nanopore which is regulated by a DNA helicase motor.

Due to the wide application of wearable electronic devices in daily life, research into flexible electronics has become very attractive. Recently, various polymer-based sensors have emerged with great sensing performance and excellent extensibility. It is well known that different structural designs each confer their own unique, great impacts on the properties of materials. For polymer-based pressure/strain sensors, different structural designs determine different response-sensing mechanisms, thus showing their unique advantages and characteristics. This paper mainly focuses on polymer-based pressure-sensing materials applied in different microstructures and reviews their respective advantages. At the same time, polymer-based pressure sensors with different microstructures, including with respect to their working mechanisms, key parameters, and relevant operating ranges, are discussed in detail. According to the summary of its performance and mechanisms, different morphologies of microstructures can be designed for a sensor according to its performance characteristics and application scenario requirements, and the optimal structure can be adjusted by weighing and comparing sensor performances for the future. Finally, a conclusion and future perspectives are described.

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