Background Preoperative prediction of early recurrence (ER) of hepatocellular carcinoma (HCC) plays a critical role in individualized risk stratification and further treatment guidance. Purpose To investigate the role of radiomics analysis based on multiparametric MRI (mpMRI) for predicting ER in HCC after partial hepatectomy. Study Type Retrospective. Population In all, 113 HCC patients (ER, n = 58 vs. non‐ER, n = 55), divided into training (n = 78) and validation (n = 35) cohorts. Field Strength/Sequence 1.5T or 3.0T, gradient‐recalled‐echo in‐phase T1‐weighted imaging (I‐T1WI) and opposed‐phase T1WI (O‐T1WI), fast spin‐echo T2‐weighted imaging (T2WI), spin‐echo planar diffusion‐weighted imaging (DWI), and gradient‐recalled‐echo contrast‐enhanced MRI (CE‐MRI). Assessment In all, 1146 radiomics features were extracted from each image sequence, and radiomics models based on each sequence and their combination were established via multivariate logistic regression analysis. The clinicopathologic‐radiologic (CPR) model and the combined model integrating the radiomics score with the CPR risk factors were constructed. A nomogram based on the combined model was established. Statistical Tests Receiver operating characteristic (ROC) curve analysis was used to evaluate the discriminative performance of each model. The potential clinical usefulness was evaluated by decision curve analysis (DCA). Results The radiomics model based on I‐T1WI, O‐T1WI, T2WI, and CE‐MRI sequences presented the best performance among all radiomics models with an area under the ROC curve (AUC) of 0.771 (95% confidence interval (CI): 0.598–0.894) in the validation cohort. The combined nomogram (AUC: 0.873; 95% CI: 0.756–0.989) outperformed the radiomics model and the CPR model (AUC: 0.742; 95% CI: 0.577–0.907). DCA demonstrated that the combined nomogram was clinically useful. Data Conclusion The mpMRI‐based radiomics analysis has potential to predict ER of HCC patients after hepatectomy, which could enhance risk stratification and provide support for individualized treatment planning. Evidence Level 4. Technical Efficacy Stage 4.
Background Biliary adenofibroma (BAF) is a rare primary hepatic tumor with the potential risk of malignant transformation. Given the extreme rarity of the disease, the imaging features of BAF are unclear. We presented a case of malignant BAF and conducted a systematic literature review. We highlighted the key imaging features in the diagnosis and aggressiveness assessment of BAF, as well as the role of various imaging modalities in evaluating BAF. Case presentation We reported a 64-year-old woman with a 5-months history of pain in the right upper quadrant abdomen. US of the liver showed a hypoechoic subcapsular nodule. CT scan revealed a subcapsular solid-cystic mass in segment V of the liver. The mass showed a marked enhancement in the arterial phase followed by wash-out in the venous phase. The patient underwent partial resection of liver’s right lobe. The mass was diagnosed as BAF with malignant transformation by postoperative pathology. Conclusions CT and MRI are helpful in recognizing and characterizing BAF. The imaging features of BAF include a solitary, large solid-cystic mass with a well-defined margin, lobulated shape, and internal septa; subcapsular location; no intrahepatic bile duct communication; the presence of von Meyenberg complexes in background liver. The enhancement patterns may have the potential to assess the aggressiveness of BAF, and that marked enhancement in the arterial phase followed by wash-out in the venous phase is suggestive of malignant BAF.
Background Localized biphasic MPeM is rare in clinical practice, we reviewed 8 cases of localized biphasic MPeM (including our present case), and summarized the clinical and imaging features of the disease. Case presentation We reported a 79-year-old man with chief complaint of a narrowing in the caliber of the stool for one year. A soft tissue shadow was occasionally found by CT examination in the right pelvic wall, and it was diagnosed as localized biphasic malignant peritoneal mesothelioma (MPeM) by postoperative pathology. Radical excision was performed and no radio-chemotherapy was applied. Nearly six years after surgery, the mass was significantly enlarged, and the neighboring tissues including rectum, prostate, seminal vesicle, and right ischial ramus were all infiltrated. The patient was in the end stage of cancer with poor prognosis. Conclusions The localized biphasic MPeM may show following characteristics: (1) with heterogeneous low-density and obscure margin; (2) with low incidence rate of ascites; (3) with few central hemorrhage and necrosis; (4) with few calcified structures; (5) with mild to moderate heterogeneous delayed enhancement on contrast-enhanced CT. The imaging characteristics can provide further information for the diagnosis of localized biphasic MPeM in the future.
Post‐combustion flue gas (mainly containing 5–40% CO2 balanced by N2) accounts for about 60% global CO2 emission. Rational conversion of flue gas into value‐added chemicals is still a formidable challenge. Herein, this work reports a β‐Bi2O3‐derived bismuth (OD‐Bi) catalyst with surface coordinated oxygen for efficient electroreduction of pure CO2, N2, and flue gas. During pure CO2 electroreduction, the maximum Faradaic efficiency (FE) of formate reaches 98.0% and stays above 90% in a broad potential of 600 mV with a long‐term stability of 50 h. Additionally, OD‐Bi achieves an ammonia (NH3) FE of 18.53% and yield rate of 11.5 µg h−1 mgcat−1 in pure N2 atmosphere. Noticeably, in simulated flue gas (15% CO2 balanced by N2 with trace impurities), a maximum formate FE of 97.3% is delivered within a flow cell, meanwhile above 90% formate FEs are obtained in a wide potential range of 700 mV. In‐situ Raman combined with theory calculations reveals that the surface coordinated oxygen species in OD‐Bi can drastically activate CO2 and N2 molecules by selectively favors the adsorption of *OCHO and *NNH intermediates, respectively. This work provides a surface oxygen modulation strategy to develop efficient bismuth‐based electrocatalysts for directly reducing commercially relevant flue gas into valuable chemicals.
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