This study revealed that excessive norepinephrine in pheochromocytoma and paraganglioma was associated with increased blood pressure and LV mass. The LV longitudinal strain was decreasing with increase in blood pressure and LV mass index. The enhanced LV circumferential strain might be the mechanism of compensation to maintain the normal LVEF in these patients.
Background: Endometrial carcinoma (EC) is a common gynecological malignancy. Vaginal cuff brachytherapy (VBT) is an adjuvant treatment for EC. Because a single-channel cylinder sometimes delivers inadequate dose coverage to the vaginal apex, three-dimensional (3D)-printing technology can be used to achieve satisfactory dose
distribution. Here, we report the first case of an EC patient with Herlyn-Werner-Wunderlich syndrome (HWWS) treated with VBT using 3D-printed applicators.
Case presentation: Here, we present a case study of endometrial cancer patient with Herlyn‑Werner‑Wunderlich syndrome who underwent surgery. During adjuvant radiotherapy, 3D-printed applicators were used in vaginal cuff brachytherapy. To accomplish the reconstruction of the source pathways on MRI, catheters with copper sulfate were placed in two 3D-printed applicators. The early tolerance of this treatment was positive. During the 6-month follow-up, locoregional recurrence was not detected.
Conclusions: Our findings strongly indicate that VBT with 3D-printed applicators may be a reasonable treatment option for EC with HWWS.
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