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Acute lymphocytic leukemia (ALL) is a deadly cancer that not only affects adults but also accounts for about 25% of childhood cancers. Timely and accurate diagnosis of the cancer is an important premise for effective treatment to improve survival rate. Since the image of leukemic B-lymphoblast cells (cancer cells) under the microscope is very similar in morphology to that of normal B-lymphoid precursors (normal cells), it is difficult to distinguish between cancer cells and normal cells. Therefore, we propose the ViT-CNN ensemble model to classify cancer cells images and normal cells images to assist in the diagnosis of acute lymphoblastic leukemia. The ViT-CNN ensemble model is an ensemble model that combines the vision transformer model and convolutional neural network (CNN) model. The vision transformer model is an image classification model based entirely on the transformer structure, which has completely different feature extraction method from the CNN model. The ViT-CNN ensemble model can extract the features of cells images in two completely different ways to achieve better classification results. In addition, the data set used in this article is an unbalanced data set and has a certain amount of noise, and we propose a difference enhancement-random sampling (DERS) data enhancement method, create a new balanced data set, and use the symmetric cross-entropy loss function to reduce the impact of noise in the data set. The classification accuracy of the ViT-CNN ensemble model on the test set has reached 99.03%, and it is proved through experimental comparison that the effect is better than other models. The proposed method can accurately distinguish between cancer cells and normal cells and can be used as an effective method for computer-aided diagnosis of acute lymphoblastic leukemia.

Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME) are two common retinal diseases for elder people that may ultimately cause irreversible blindness. Timely and accurate diagnosis is essential for the treatment of these diseases. In recent years, computer-aided diagnosis (CAD) has been deeply investigated and effectively used for rapid and early diagnosis. In this paper, we proposed a method of CAD using vision transformer to analyze optical coherence tomography (OCT) images and to automatically discriminate AMD, DME, and normal eyes. A classification accuracy of 99.69% was achieved. After the model pruning, the recognition time reached 0.010 s and the classification accuracy did not drop. Compared with the Convolutional Neural Network (CNN) image classification models (VGG16, Resnet50, Densenet121, and EfficientNet), vision transformer after pruning exhibited better recognition ability. Results show that vision transformer is an improved alternative to diagnose retinal diseases more accurately.

In complex industrial processes, it is necessary to perform modeling analysis on some industrial systems and find and optimize the factors that have the greatest impact on the results, in order to achieve the optimization of the industrial systems. However, due to the high-level nature or complex working mechanism of complex industrial systems, traditional principal component analysis methods are difficult to apply. Therefore, this paper proposes a characteristic model-based principal component analysis (CMPCA) to perform principal component analysis on complex industrial systems. The differential pressure flowmeter is taken as an example to verify the effectiveness of the method. Flowmeter is an indispensable instrument in measurement, and its accuracy depends on its own structural parameters. However, the measurement accuracy of some flow meters is not high, and the measurement error is large, which affects the normal industrial production process. This method is used to analyze the influence of the structural parameters of the flowmeter on its measurement accuracy, and the four most important structural parameters are found and optimized. The measurement error of the Bitoba flowmeter is reduced from 1% to 0.2%, and the measurement repeatability is reduced from 0.3 to 0.06, which proves the effectiveness of the method.

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