In order to meet the demands for the electric field measurement along the composite insulators simultaneously, such as intensive signal, fine insulation, passive and small size, a novel measurement system based on the core device, the integrated electro-optic sensor, was developed. First, the theory of the system and the sensor were introduced. Second, after fabrication, the input/output character was obtained and the calibration was implemented between two parallel square metal planes under power frequency. By optimum design, this kind of novel sensor was suitable for insulated, intensive (> 250 kV/m), small size (55 mm x 2 mm x 1 mm) electric field measurement. Third, the axial and radial electric field distribution of the insulators were measured carefully in laboratory, and by combining the BEM and CSM method, the electric field of the same insulators was numerically calculated. Finally, the measurement and calculated results of electric field distribution were compared and the relationship between them were analyzed. This comparison verified the suitability and importance of the measurement system. Index Term -composite insulators, electric field measurement, integrated electro-optic field sensor, BEM, CSM.Rong Zeng (M'02, SM'06) was born in Shaanxi, China in 1971. He received the B.Sc., M. Eng., and Ph.D. degrees from the Department of Electrical Engineering, Tsinghua University in Beijing, respectively in 1995Beijing, respectively in , 1997Beijing, respectively in , and 1999. He became a lecturer in the Department of Electrical Engineering, Tsinghua university in Beijing in 1999, and an associate professor in 2002. Now he is vice dean of the Electrical Engineering Department, Tsinghua University. He is currently working in the fields of lightning and grounding research, lightning protection, and electromagnetic compatibility (EMC) in power system, with main emphasis on the hybrid research of electric and magnetic field measurement by integrated optical sensor and numerical simulation of long air gap discharge process. He is the author and coauthor of more than 20 IEEE transaction papers.

Most randomized trials for acute promyelocytic leukemia (APL) have investigated highly selected patients under idealized conditions, and the findings need to be validated in the real world. We conducted a population-based study of all APL patients in Zhejiang Province, China, with a total population of 82 million people, to assess the generalization of all-trans retinoic acid (ATRA) and arsenic as front-line treatment. The outcomes of APL patients were also analyzed. Between January 2015 and December 2019, 1,233 eligible patients were included in the final analysis. The rate of ATRA and arsenic as front-line treatment increased steadily from 66.2% in 2015 to 83.3% in 2019, with no difference among the size of the center (≥5 or <5 patients per year, p = 0.12) or age (≥60 or <60 years, p = 0.35). The early death (ED) rate, defined as death within 30 days after diagnosis, was 8.2%, and the 3-year overall survival (OS) was 87.9% in the whole patient population. Age (≥60 years) and white blood cell count (>10 × 109/L) were independent risk factors for ED and OS in the multivariate analysis. This population-based study showed that ATRA and arsenic as front-line treatment are widely used under real-world conditions and yield a low ED rate and a high survival rate, which mimic the results from clinical trials, thereby supporting the wider application of APL guidelines in the future.

No abstract

No abstract