Herein, we developed an efficient and green method for the synthesis of various alkyl amines via C(sp3)−S bond cleavage of vinylsulfonium salts. The reaction proceeds under an air atmosphere with...
A procedure for the synthesis of 1,2-diamines from vinyl
sulfonium
salts and arylamines under mild conditions was developed. This present
synthetic protocol not only obviates the need for a transition-metal
catalyst and an oxidizing reagent but also features a broad substrates
scope. The practicability of this protocol is demonstrated by the
one-pot synthesis, a scale-up reaction, and transformations of the
products to diverse N-heterocyclic compounds. Mechanistic
studies indicate that the formation of aziridine plays a key role
during this diamination process.
Metal-free allylic C(sp3)−H alkylation of branched α-styryl sulfonium salts based on [2,3]-sigmatropic rearrangement strategies has been developed. This operationally simple protocol enables allylic C(sp3)−H alkylation of a wide range of...
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