Background. The therapy of patients with concomitant multiple sclerosis and ankylosing spondylitis is a challenge for clinicians. Secukinumab has been shown to be effective in the treatment of multiple sclerosis. In the clinical case we present, substantial clinical and radiological remission in the case of both autoimmune diseases was observed. Case presentation. A male adult was diagnosed with relapsingremitting multiple sclerosis. The patient complained of severe thoraco-lumbar pain. Magnetic resonance imaging led to a diagnosis of ankylosing spondylitis. Considering that nonsteroidal anti-inflammatory drugs were ineffective and TNF-alfa blockers are contraindicated in patients with multiple sclerosis, secukinumab was prescribed. Magnetic resonance imaging 8 months after initiation of therapy provided clinical stability in consideration of the two autoimmune comorbidities. Conclusions. Secukinumab is an effective therapy of concomitant multiple sclerosis and ankylosing spondylitis.
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