Effect of different concentrations 5% and 10% of white, black rice (Oryza sativa, L. indica) and their mixtures as powder on biological and biochemical changes of hypercholesterolemic rats were investigated. Forty-eight white male albino rats weighing 140±10g were used and divided to 8 groups, each group (6) rats. Rats infected of hypercholesterolemic by injected with Triton-X-100 (100mg/ kg body weight). Glucose, serum liver functions (GOT GPT and ALP), T.G, T.C, LDL-c, HDL-c, VIDL-c, AIT, kidney functions (uric acid, urea and creatinine) were determined. Also, identification of phenolic compounds were determined using HPLC technique. The obtained results of hypercholesterolemic rats revealed that white, black rice as powder improve serum glucose level, liver functions, kidney functions and lipid profile in rats especially 10% black rice powder. The HPLC results showed that the black rice had higher bioactive compounds than white rice, besides the fact that it has so many health benefits.
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