Background: One of the most frequent reasons of heel discomfort is plantar fasciitis. A thick band of tissue from the heel bone to the toes on the bottom of each foot experiences degeneration and, to a lesser extent, inflammation. Though it can also be brought on by prolonged standing or rising from a chair, the discomfort is typically at its greatest when taking the first few steps after waking up. It tends to occur more often in women, middle-aged, athletes, and the obese. Objective: To have overview about treatment lines of Plantar fasciitis. Methods: We looked for data on Plantar fasciitis and treatment in medical journals and databases like PubMed, Google Scholar, and Science Direct. However, only the most recent or extensive study was taken into account between 2000 and 2013. References from related works were also evaluated by the writers. There are not enough resources to translate documents into languages other than English, hence those documents have been ignored. It was generally agreed that documents such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations did not qualify as legitimate scientific study Conclusion: It can be treated either by conservative treatment such as rest, analgesics and stretching exercises that are successful in majority of cases. However, cases not responding to conservative treatments for more than 3 months, they can be treated with minimal invasive treatment such as corticosteroids, botulinum toxin or platelet-rich plasma (PRP) injections. Surgical intervention is often considered after failure of conservative treatments for more than 6 months. The most popular surgical procedures for refractory fasciitis are gastrocnemius recession and plantar fasciotomy.
Nitroglycerin, a vasodilator, is typically used to treat anginal chest discomfort. The FDA currently approves it for the acute prophylaxis of angina pectoris owing to coronary artery disease (CAD) as well as the acute alleviation of an episode. The treatment of hypertensive urgency/emergency, coronary artery spasm, cocaine-related angina, congestive heart failure (CHF), and chronic anal fissures are a few of the unapproved, off-label uses for this medication. In order for medical professionals to successfully direct patient therapy in circumstances where nitroglycerin is advantageous to patient care, the present review describes the indications, mechanism of action, routes of administration, significant adverse effects, contraindications, monitoring, and toxicity of nitroglycerin.
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