The study included 60 diabetic patients (30 patients type 2 diabetes mellitus complicated with diabetic retinopathy (DR) and 30 patients T2DM not complicated with DR). The study also included 30 healthy control individuals defended as subjects who apparently haven’t any chronic diseases. investigations were done including IL-6 and serum omentin-1. Fundus examination was carried out by an expert ophthalmologist. The study showed that the lowest mean of serum omentin-1 was recorded (P<0.05) in DR patients (687 pg/ml), and the highest (P<0.05)was in the control group (3540.625 pg/ml), The study also demonstrated that there was a significant decrease (P<0.05) in DM patients (991.2 pg/ml). The study also showed that serum IL-6 was increased significantly(P<0.05) in DR patients (253.7 pg/ml) as compared with the control group (35.33 pg/ml), The study also showed that serum IL-6 was increased significantly (P<0.05) in DM patients (102.5 pg/ml). The study showed negative correlation of serum omentin-1 concentrations with IL-6 in DR patients.
The study included 60 diabetic patients (30 patients with type 2 diabetes mellitus complicated with diabetic retinopathy (DR) and 30 patients with T2DM not complicated with DR). The study also included 30 healthy control individuals defended as subjects who apparently haven’t any chronic diseases. Fundus examination was carried out by an expert ophthalmologist. The study showed that the highest mean of serum MDA was recorded (P<0.05) in DR patients (55.96 ng/ml) and DM patients (37.86 ng/ml), the lowest (P<0.05) was in the control group gave an MDA (16.94 ng/ml). also demonstrated that there was the lowest mean of serum SOD was recorded (P<0.05) in DR patients (10.056 IU/ml) and the highest was (P<0.05) in the control group gave a SOD (42.865 IU/ml) While it also recorded a significant decrease (P<0.05) for DM patients (12.64 IU/ml). Additionally, the level of serum GSH was reduced significantly (P<0.05) in DR patients (1.100 ug/mL) as compared with the control group (14.745 ug/mL), which also showed that serum GSH was reduced significantly(P<0.05) in DM patients (2.766 ug/mL). Furthermore, the level of serum zinc was reduced significantly (P<0.05) in DR patients (33.6 ug/dL) as compared with the control group (98.5 ug/dL).
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