This research was carried out to survey the ffects of dietary of Lentinula edodes mushroom extract as a feed supplement on growth performance and survival rate, immune response, hematological and biochemical characteristics of beluga juvenile (Huso huso). Four hundred and fifty fish after acclimation with average weight of 40.45 ± 5.72 g were fed in a wholly randomized design in 5 treatments (basic diet containing 0% (control), 00.5%, 1%, 1.5% and 2% L. edodes mushroom extract) and 3 replicates. During the experiment (56 days), a total of eight samples were taken in 8 weeks. The mean of data were analyzed using oneway ANOVA and Duncan's post hoc test at 5% level. Results indicated that administration of 2% of mushroom extract for 8 weeks improved weight gain, specific growth rate and feed conversion ratio of beluga (P<0.05).
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