Introduction: Bone-specific alkaline phosphatase (BALP) has been a sensitive and reliable marker of bone metabolic activity. The study aimed to study the epidemiology of orthopaedic trauma patients and estimate the level of BALP in these patients.Material and methods: This hospital-based observational cross-sectional study was conducted on over 300 patients admitted to the orthopaedic trauma unit in the level I trauma centre of North India during the study period from January 2020 to January 2021. The level of BALP was assessed in serum samples of 258 patients.Result: A total of 300 patients were included in this study, with an average age of 33.52±17.16 years. Road traffic accidents were the most common mode of injury among admitted patients. We found a significant linear correlation between age and mean BALP levels (P-value < 0.005). The mean age of patients having abnormal BALP is 63.0±16.61 years. Females (22.61±16.23) had greater mean BALP levels than males (13.15±5.86). Among different fractures, fractures around the hip had a higher mean BALP level (23.17±15.07). Patients with diabetes mellitus have higher mean BALP levels.Conclusion: BALP is a cost-effective, readily available bone marker to assess the metabolic activity of orthopaedic trauma patients. Old age patients should undergo routine BALP estimation at admission to rule out metabolic disorders, and timely intervention will prevent complications associated with metabolic disorders.
Taurine chemically known as 2 aminoethanesulfonic acid; NH2CH2CH2SO3H it’s a non essential amino acid, due to absence of carboxyl group it does not participate in protein synthesis, it does not metabolized and thus not involved in gluconeogenesis, thereby not constituting a direct energy source, This wonderful molecule was discover in 1827 by two German scientist Tiedemann and Gmelin from bile of ox (Bos taurus), Ten years later, this amino acid got its name as Taurine by Demarcay, and 20 years later Jacobsen and Smith discovered that its structure contains sulfur. In a wide variety of invertebrate and vertebrate tissues the natural occurrence of taurine has been recognized, It is also present in plants algae and fungi. In this review we try to cover all possible beneficial role of taurine.
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