A nitrogen-doped carbon supported nanocobalt catalyst was developed and successfully applied for the hydrogentransfer coupling of quinolinium salts and tetrahydroquinoline compounds. The selective coupling of the C6 sites of tetrahydroquinolines (THQs) with the α sites of quinoline salts generated a series of 2-substituted N-alkyl-tetrahydroquinolines. This catalytic conversion method, which can be employed to synthesize various functionalized tetrahydroquinolines, has several advantages that include excellent hydrogen transfer selectivity, a reusable and inexpensive catalyst, and environmental friendliness. Letter pubs.acs.org/OrgLett
A copper-catalyzed acylhalogenation reaction of 3-methylanthranils with acid halides, which utilizes the acyl halide as both the acylating and halogenating source, is described. This process involves NÀ O/ CÀ H/CÀ X bond cleavages and CÀ N/CÀ X bond formations to furnish N-(2-(2-haloyl)phenyl)amides. Furthermore, this difunctional conversion using the NÀ O bond and oxygen as oxidants displays good tolerance for different functional groups.
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