Objectives: To determine the level of depression , anxiety and stresss in pathologists due to Covid -19 pandemic . Materials and methods: It was a Cross sectional Analytical Multicenter Questionnaire based study conducted from April 2020 to June 2020 by including Pathologists working in Khyber Teaching Hospital and Pakistan Institute of Medical Sciences , Islamabad. Informed written consent was obtained and DASS-21 Questionnaire was administred .Data was analysed by SPSS. Levels of depression, anxiety and stress were determined and analysed by multiple regression to predict depression anxiety and stress levels from demographics. Results: Mean age of the study sample was 25-63 (37±8.75).There were 13(22.4%) males and 45(77.6%) females. Overall DAS score, mean depression , anxiety and stress score were 31.5±22, 8.7±9.1, 7.4±7.1 and 15.3±9 respectively. Females had higher overall DAS score (U=156.5, p=.011), depression score (U=178.5, p=.032) and anxiety score (U=168.5, p=.029) as compared to males. Anxiety scores were highest in pathologists working in microbiology section and lowest in those of chemical pathology section (?2=8.13,p=.043). Multiple regression analysis showed that female gender was significantly associated with a higher overall DAS sore (?=13.69 , p=.047) and stress score (?=6.10 , p=.031) as compared to male gender. Conclusion: Pathologists working in Covid-19 pandemic have a high level of mental distress and females have higher level of psychological distress as compared to males. Implementation of mental support programmes for health care workers during pandemic situations is required to provide psychological support to health care workers.
Background: Hematological disorders are found commonly in the general population existing on both ends of the spectrum with minute disorders like iron deficiency anemia to as severe as bone marrow infiltration Objective: To assess the frequency of hematological malignancies based on bone-marrow aspiration and trephine biopsy in patients presenting to tertiary care hospital Methodology: The current study was cross-section descriptive study carried out at the Pathology department of Bacha Khan Medical College, Mardan from April 2013 to October 2021. Bone-marrow aspiration and trephine biopsy was done for all the patients. Data regarding gender, age, clinical examination and diagnosis was recorded on a proforma designed for this research. Results were analyzed by using IBM SPSS (version 23). Results: In our study, a total of 182 patients were included. The mean age (±SD) in the current study was 41 (12.6) years. Based on the malignant hematological disorder, acute myelogenous leukemia was diagnosed in 15 (23.08%) patients, acute lymphoblastic leukemia in (23.08%) patients, chronic myeloid leukemia in 14 (21.54%) patients, acute leukemias in 3 (4.62%) patients, Myeloproliferative neoplasms in 6 (9.23%) patients, Lymphoproliferative disease in 11 (16.92%) patients while plasma cell myeloma was diagnosed in 1 (1.54%) patients. Conclusion: Our study concludes that acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL) is the most common hematological malignancies in Bacha Khan Medical College followed by chronic myeloid leukemia (CML) which is the second highest malignancies in Bacha Khan Medical College in this specific time. Keywords: hematological malignancies, bone-marrow aspiration, trephine biopsy
Objective: To evaluate the pattern of changes in the platelet indices in different Leukemias. Material and method: This descriptive cross-sectional study was conducted in the Pathology Department of Khyber Teaching Hospital from January 2021 to December 2021 (1-year duration). Diagnosed acute and chronic leukemia cases were included while those receiving therapeutic chemotherapy were excluded. The platelet count was analyzed as a part of complete blood counts by the Sysmex Hematology analyzer in the Hematology section of the Pathology department. The changes observed in the platelet counts in different types of leukemia were recorded in a proforma. Mean, standard deviation, frequency and percentages were used to compute variables. Results: The age range of the 100 included cases of leukemia was 01 - 50 years. The mean age of the study population was 30 ± 10 SD years. Platelet count was low in acute Leukemias and chronic lymphocytic leukemia. Only in chronic myeloid leukemia, raised platelet count was seen (in 62% of cases). Mean platelet volume and platelet distribution width were decreased in all leukemias. Conclusion: Platelet indices are decreased in Leukemias, with the exception of chronic myeloid leukemia where platelet count is raised. Keywords: Platelet count, Acute lymphoid leukemia, Acute myelogenous leukemia, Chronic lymphocytic leukemia, Chronic myelogenous leukemia.
Objectives: This study was conducted with the aim to highlight the clinic-pathological profile of patients with dengue fever in Peshawar. Materials and methods: It was a cross-sectional study conducted at Khyber Teaching Hospital, Peshawar from September 2021 to January 2022. All cases with positive Dengue serology as done by ICT kit were included in the study. Cases with significant symptoms of Dengue but negative serology were excluded from the study. Clinical data and results of liver function tests were recorded. Mean and standard deviation was used for quantitative data while frequency and percentages were used for qualitative data. Results: About 100 diagnosed cases of dengue fever were included. Seventy-four (74%) cases had dengue fever, while 24 (24%) cases had dengue hemorrhagic fever. About 2 (2%) cases had dengue shock syndrome. Serum Alanine transaminase level was abnormal in most of the cases. Conclusion: The study reveals that the majority of the cases of dengue fever have mild to moderate disease. Severe disease was seen in a very small proportion of patients. Keywords: Dengue hemorrhagic Fever, Liver Function Tests, Platelets count.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.