Introduction: Dieulafoy lesion (DL) is a rare yet potentially life-threatening cause of acute gastrointestinal bleeding. There is a paucity of research on the impact of sociodemographic indices on DL hospitalization outcomes. This study aimed to describe the epidemiologic trends and effects of sociodemographic disparities on outcomes among DL hospitalizations over a decade. Methods: We queried Nationwide Inpatient Sample (NIS) databases from 2010 to 2019, identified hospitalizations with DL, and excluded those of patients less than 18 years. We obtained the incidence and admission rate of DL per 1,000,000 adult hospitalizations for each year. We analyzed trends in mortality rate, mean length of hospital stay (LOS), and mean total hospital charge (THC). We highlighted disparities in outcomes stratified by sex, race, and mean household income (MHOI) quartile. We used multivariable regression analysis to obtain trends in incidence and admission rates, mortality, LOS, and THC adjusted for age categories, sex, and race. We used Joinpoint regression analysis to obtain trends in adjusted rates. Threshold for statistical significance was set at 0.05. Results: Of the 305 million hospitalizations included in our study, 59,862 were complicated by DL, with 40,356 principal admissions for DL. On Joinpoint analysis, there was no trend in adjusted incidence rate (p 5 0.1) or adjusted admission rate (p 5 0.05) over the study period. There was also no trend in adjusted mortality rate among all hospitalizations with DL (p trend 5 0.855), admissions with principal diagnosis of DL (p trend 5 0.754) or adjusted LOS (p trend 5 0.879) but there was a US$4,011 increase in adjusted THC (p trend , 0.001).Middle-aged adults had increased odds of mortality (adjusted odds ratio, aOR 5 1.48) compared to young adults (p 5 0.046). Females had 16% lower odds of adjusted mortality (p trend 5 0.046), 0.67 days reduction in adjusted LOS (p trend 5 0.001), and US$16,905 reduction in adjusted THC (p trend , 0.001) compared to males. Blacks had 2.6 days increase in adjusted LOS and US$33,685 increase in adjusted THC (both p trends , 0.001) compared to Whites. Hispanics had increased odds of mortality (aOR 5 1.76), 1.5 days increase in adjusted LOS, and US$50,476 increase in adjusted THC compared to Whites ((p trends 5 0.018, 0.003 and , 0.001 respectively) (Figure ). Conclusion: Outcomes of DL hospitalizations were worse in middle-aged adults, males, and ethnic minorities. Further studies may be needed to elucidate the reasons behind these findings.[0692] Figure 1. Trends in mortality rates among hospitalizations with DL and admissions with principal admitting diagnosis of DL.
ObjectivesPancreatic mass lesions are often solitary, although rarely synchronous pancreatic masses are encountered. No study has compared synchronous lesions with solitary lesions in the same population. The aim of the present study was to determine the prevalence, clinical, radiographic, and histologic findings of multiple pancreatic masses on consecutive patients undergoing endoscopic ultrasound (EUS) for pancreatic mass lesion.MethodsAll patients undergoing EUS for pancreatic mass lesions with histologic sampling over a 5-year span were identified. Charts were abstracted for demographics, medical history, radiographic findings, EUS findings, and histology and were reviewed.ResultsA total of 646 patients were identified, of which 27 patients (4.18%) had more than 1 pancreatic mass on EUS or cross-sectional imaging. The 2 groups were comparable with each other in terms of demographic factors and medical history. The 2 cohorts were comparable in location of the largest pancreas lesion and EUS characteristics. Patients with synchronous mass lesions were more likely to have metastatic lesions (P = 0.01). No other differences in histology were noted between the 2 groups.ConclusionsPatients with multiple pancreatic mass lesions were more likely to have metastatic lesions compared with patients with solitary lesions.
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