Background and aims:Patients with Inflammatory Bowel Disease (IBD) suffer from different level of bone diseases in density and architectures. This study has been designed to measure Bone Mineral Density (BMD) and Trabecular Bone Score (TBS) in IBD patients, Golestan province, northeast of Iran. Materials and methods:In this cross-sectional study during January 2018 to August 2018, 69 patients with IBD (UC=57 and Crohn’s disease=10; male: female 0.74; mean age, 39 years) recruited from the IBD registry in Golestan Research Center of Gastroentrology and Hepatology. After taking the informed consent, all patients have been interviewed by a trained physician and a questionnaire has been completed. Trabecular bone score (TBS) was performed using lumbar spine dual X-ray absorptiometry (DXA) images. After entering data into the SPSS-16 software, analysis was done using X2 and non-parametric tests.Results:Normal BMD (T Score>-1) was reported in 19 patients, low bone mass (-1 <T Score< -2.5) in 18 and osteoporosis (T Score <-2.5) in 4 patients. TBS results showed that 5 patients had partially degraded microarchitecture and 5 had fully degraded microarchitecture.Conclusion:In the present study on IBD patients, age, BMI, waist circumference and abdominal circumference had been correlated significantly with bone weakness. The duration of disease was correlated significantly with FRAX. The duration of disease was also correlated significantly with risk of major osteoporotic fracture in 10-years (FRAX adjusted MOF).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.