Background: About 10-15% of population HBV infection becomes chronic, and 85-90% are resolved. In Iraq, HBs-Ag assay by ELISA is only mandatory test for detection of HBV infection in blood donors. Anti- HBc and anti-HBs were not detectable in their sera.Objective: To investigate the distribution of serological patterns for HBV who were HBsAg negative.Material and method: Between July 18, 2011 to December 25, 2011, 10ml of blood samples were collected from National blood Transfusion Center donors, Baghdad, for 25782 individuals (25294 male, 488 female), mean age (20-65)years. HbsAg positive sera excluded (185), and final number of donors included in thestudy was 25597 HbsAg negative.Result: The data showed a previous exposure for HBV(p>0.05) through anti-HBc and anti-HBs 3.8% by Architect system. The anti-HBs combine with anti-HBc was 68.5%, while anti-HBc alone was 31.5%. Independent risk factors were association with married, history of blood transfusion and residence.Conclusion: The prevalence of the HBV in Iraq is 4.6% as intermediate region at first time.
The Rh(D,C,c,E,e) were typed in a sample consisted of 378 individuals, one hundred of them present the control whereas the remaining 278 individuals were affected by β-thalassemia. The last group was divided into three types; 156 of individuals affected with major thalassemia, 66 of individuals affected with intermediate thalassemia and 56 of individuals affected with minor thalassemia (carriers).The aim of the present study is to find any genetic variation in the distribution of Rh blood group system between thalassemia and control groups. The various comparisons lead to a significant difference in Rh group for β-thalassemia and all its subtypes except the minor one, because of the decrease in resistant phenotype CCDee and increase in CcDEe phenotype. It is clear, the importance of the Rh blood group since it can be considered as a source for detecting the risk of inheritance for β-thalassemia and / or the probability of its expression. It can be used with the other laboratory tests in genetic counseling. This study, recommended to do more studies about the other blood groups in order to know about its phenotypic frequencies between healthy and disease samples
Background: About 10-15% of population HBV infection becomes chronic, and 85-90% are resolved. In Iraq, HBs-Ag assay by ELISA is only mandatory test for detection of HBV infection in blood donors. Anti-HBc and anti-HBs were not detectable in their sera. Objective: To investigate the distribution of serological patterns for HBV who were HBsAg negative. Material and method: Between July 18, 2011 to December 25, 2011, 10ml of blood samples were collected from National blood Transfusion Center donors, Baghdad, for 25782 individuals (25294 male, 488 female), mean age (20-65)years. HbsAg positive sera excluded (185), and final number of donors included in the study was 25597 HbsAg negative. Result: The data showed a previous exposure for HBV(p>0.05) through anti-HBc and anti-HBs 3.8% by Architect system. The anti-HBs combine with anti-HBc was 68.5%, while anti-HBc alone was 31.5%. Independent risk factors were association with married, history of blood transfusion and residence. Conclusion: The prevalence of the HBV in Iraq is 4.6% as intermediate region at first time.
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