Anticipation of complete reconstruction of lost periodontal tissues destroyed by periodontal disease is still a major challenge. Flap design in
periodontal regeneration procedure should be such that to preserve maximum tissue and allow complete stabilization of the graft placed. Bone
grafts are used in the treatment of various maxillomandibular bone defects, including Intrabony defects and Furcation defects. Allografts such as
DFDBA, FDBA, amnion membrane, chorion membrane and amnion-chorion membrane are processed and stored according to standard protocols
in central tissue bank, MAIDS New Delhi. The purpose of this case report is to describe and evaluate the efcacy of the “whale's tail” technique that
was designed for the treatment of wide intrabony defects in the esthetic zone. Indigenously prepared DFDBA bone allograft and amniotic
membrane used in the regeneration of osseous defect shows radiographic bone ll and pocket reduction from 7mm to 3 mm 18 months
postoperatively
The aim of this study was to determine the adverse effects of maternal nicotine treatment during pregnancy and on rat liver of newborns. Also to determine a protective effect of Trifolium Pratense seed extract against the deleterious effects of nicotine. All groups were treated from the 6 th day of gestation till parturition. The dams and their newborns were sacrificed and piece of liver from each subjected to the histological studies. The morphological findings of the newborns revealed marked signs of retardation in growth with malformations including superficial haematoma, shortened neck region, kinky tail, uni-and bilateral deformity of both fore and hind limbs and abnormal skin. The histopathological studies on the liver of the maternal nicotine treated and their newborns revealed disruption of hepatic cords arrangement. Blood sinusoids were dilated. The hepatic tissue exhibited inflammatory cells with signs of early cellular granulomatous lesions. Some hepatocytes obliterated and others with karyolysis nuclei. Kupffer cells become hypertrophied and dispersed throughout the hepatic cords. Fatty vacuoles and infiltrations were detected in many of the hepatocytes.The magnitude of these changes was dose dependent. TPSE supplementation was found to ameliorate an prevent the adverse effects of maternal nicotine treatment morphologically and histologically.
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