Månsson (1996) Mineral loss in incipient caries lesions quantified with laser fluorescence and longitudinal microradiography: A methodologic study, Acta Odontologica Scandinavica, 54:1, 8-13To link to this article: http://dx.loss in incipient caries lesions quantified with laser fluorescence and longitudinal microradiography. A methodologic study. Acta Odontol Scand 1996;54:8-13. Oslo. ISSN 0001-6357.

Mild traumatic brain injury (mTBI) is impossible to detect using standard neuroradiological assessment such as structural magnetic resonance imaging (MRI). Injury does however disrupt the dynamic repertoire of neural activity indexed by neural oscillations. In particular, beta oscillations are reliable predictors of cognitive, perceptual and motor system functioning, as well as correlate highly with underlying myelin architecture and brain connectivity - all factors particularly susceptible to dysregulation after mTBI. Methods: We measured local and large-scale neural circuit function using MEG (magnetoencephalography) with a data-driven model fit approach using the Fitting Oscillations & One-Over F algorithm, in a group of young adult males with mTBI and a matched healthy control group. We quantified band-limited regional power and functional connectivity between brain regions. Results: We found reduced regional power and deficits in functional connectivity across brain areas, which pointed to the well-characterized thalamocortical dysconnectivity associated with mTBI. Furthermore, our results suggested beta functional connectivity data reached the best mTBI classification performance when compared with regional power and symptom severity (measured using SCAT2, or Sport Concussion Assessment Tool 2). Conclusions: The current study revealed the relevance of beta oscillations as a window into neurophysiological dysfunction in mTBI, and also highlights the reliability of neural synchrony biomarkers in disorder classification.

The present study describes an investigation by fluorescence quenching, circular dichroism and UV-visible spectroscopy of the interaction between norfloxacin (NRF) and human serum albumin (HSA) in the presence of electromagnetic fields (EMFs). The results obtained from this study indicated that NRF had a strong ability to quench HSA at λex = 280 nm. In addition, a slight blue shift occurred, which suggested that the microenvironment of the protein became more hydrophobic after addition of NRF. The interaction between the NRF and HSA, whether in the absence or presence of an EMF, was considered to be a static quenching mechanism. Moreover, synchronous fluorescence demonstrated that the microenvironment around Trp became modified. Data of HSA-NRF in the presence of EMFs between 1 Hz–1 MHz confirmed the results of quenching and blue shifts. Corresponding Stern-Volmer plots were also drawn and the resultant Ksv and kq values were compared. Moreover, the binding parameters, including the number of binding sites, the binding constant and the distance, r, between donor and acceptor, were calculated based on Förster’s non-radiative energy transfer theory. According to far and near UV-CD, the formation of the complex caused changes of the secondary and tertiary structures of HSA. The obtained results are significant for patients who are subjected to high-frequency radiation as this was found to reduce the affinity of NRF to HSA.

RLS has an independent and significant role in sleep quality and QoL in the patients with diabetes. Neuropathy with RLS does not confer any additive burden on QoL and sleep quality of this population of patients with diabetes.