C-peptide replacement of Type I BB/Wor-rats partially prevents acute and chronic metabolic, functional and structural changes that separate Type I diabetic polyneuropathy from its Type II counterpart suggesting that C-peptide deficiency plays a pathogenetic role in Type I diabetic polyneuropathy.

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We report the visible absorption spectrum of the fluoroformyloxyl radical. The spectrum is assigned to the B 2A1–X 2B2 transition in FC(O)O. The origin of the excitation spectrum is observed at 13 150 cm−1 (760 nm). Extensive progressions in the OCO bending mode of the B state, ν′3 = 610 cm−1, dominate the spectrum. Three other progressions are observed: the OCO wag mode, ν′6 = 840 cm−1; the CF stretching mode, ν′2 = 1110 cm−1; and the asymmetric CO stretching mode, ν′4 = 2820 cm−1. Two series of hot bands also appear in the spectrum. From these bands the frequency of the OCO bending mode, ν″3 = 520 cm−1, is assigned for ground state FC(O)O. The experimental spectrum is compared to the results of ab initio MO calculations. These include second-order Mo/ller–Plesset perturbation theory (UMP2) and quadratic configuration interactions theory with single and double excitations (QCISD) for both the X 2B2 and B 2A1 states. The origin of the B 2A1–X 2B2 transition and the predicted vibrational frequencies are found to be in reasonable agreement with experiment.

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