This article describes an efficient approach for the synthesis of 5‐amino‐3‐methyl‐7‐aryl‐1,3‐dihydroisobenzofuran‐4,6‐dicarbonitrile derivatives from the reaction of aromatic aldehyde, 2‐methyltetrahydrofuran‐3‐one, and malononitrile under mild conditions. This is a simple and facile process to structure this important heterocyclic compounds. The other advantages of this approach are rapid reaction rate, high yield, and simple procedure. This article provided a good method for the synthesis of 1,3‐dihydroisobenzofuran derivatives.
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