A KI-catalyzed oxidative coupling of benzothiazoles with aryl aldehydes has been developed using TBHP as an oxidant in neat water under metal free conditions. Various 2-aryl benzothiazoles were prepared in 36-79% yields for 28 examples. The mechanistic studies suggested that this transformation proceeded via a radical process.
A metal and additive free base-mediated method for the formation of 4H-benzo[d][1,3]dioxin-4-one and its derivatives, from salicylic acids and dichloromethane, was developed using dichloromethane (DCM) and 1,1-dichloroethane (1,1-DCE) as the C1 source.
Title compounds, which are important structural units for the preparation of insecticides and multiple‐substituted benzene derivatives, are synthesized by a green and practical method starting from readily available materials.
A series of 2‐substituted benzothiazoles (III) and (V) (28 examples in all) is readily prepared by a KI‐catalyzed oxidative arylation of benzothiazoles (I) with corresponding aldehydes (II) and (IV), respectively.
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