The left ventricular mechanical model and the circulation model are important for the cardiovascular dynamics simulation that consider the characteristics of the ventricular cells and the structure of left ventricle (LV). Due to the fact that the cardiovascular dynamics is the result of nonlinear interactions between these two models, simultaneous consideration of both models using a strong coupling method is necessary for an accurate simulation. In this paper, we propose a simulation algorithm that is capable of calculating cardiovascular dynamics model by strong coupling of the left ventricular mechanical model and the circulation model.
To realize precise simulation of the left ventricular motion, it is important to utilize an accurate myocardial tissue model which can reproduce various characteristics of myocardial tissue contraction. In this study, we show that the nonlinear characteristics of the passive myocardial tissue property is the essential nature of the nonlinear force-velocity relation and present a formulation for hyperelastic physiological tissue property. Experimental results of our myocardial tissue simulation with the hyperelastic material property proposed are in good agreement with the reported force-velocity relation of real tissue.
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